Literature DB >> 31210083

Suboptimal cardiovascular risk management in rheumatoid arthritis patients despite an explicit cardiovascular risk screening programme.

M Heslinga1, Iam Van Den Oever1, D L Jonker2, E N Griep2, Hrm Griep-Wentink2, Y M Smulders3, W F Lems1,4, M Boers4,5, A E Voskuyl4, Mjl Peters3, D Van Schaardenburg1,5, M T Nurmohamed1,4,6.   

Abstract

Objective: In 2011, we started to offer cardiovascular (CV) risk screening to rheumatoid arthritis (RA) patients with a high CV risk. After 1 year, we assessed whether patients labelled as high CV risk had started preventive treatment when indicated, and whether the CV risk score had changed.
Methods: CV risk screening was performed in both a large outpatient rheumatology clinic and a general hospital in the Netherlands, and the general practitioner or the internist was informed about the results of the CV screening, including specific advice on the initiation or adjustment of cardiopreventive drugs. National guidelines were used to assess how many patients were eligible for preventive treatment. After 1 year, CV risk, lifestyle, and treatment were re-evaluated. Patients with a history of CV disease at baseline or who experienced a CV event during follow-up were excluded from the analyses.
Results: A high 10 year CV risk (> 20%) was present in 58%, and 55% had an indication for anti-hypertensives, statins, or both. At follow-up, cardiopreventive drug treatment had been started or adjusted in only one-third of patients with an indication for treatment. After screening, 42% of patients reported having changed their lifestyle, through more exercise (24%), diet adaption (20%), and weight loss (11%).
Conclusion: Despite clear guidelines to improve CV risk, the results of a programme comprising active screening, targeted advice, and referral to the general practitioner or internist prove that primary prevention remains a major challenge in high-risk RA patients.

Entities:  

Year:  2019        PMID: 31210083     DOI: 10.1080/03009742.2019.1600718

Source DB:  PubMed          Journal:  Scand J Rheumatol        ISSN: 0300-9742            Impact factor:   3.641


  5 in total

1.  Exercise intervention on cardiorespiratory fitness in rheumatoid arthritis patients with high cardiovascular disease risk: a single-arm pilot study.

Authors:  M Sobejana; J van den Hoek; G S Metsios; G D Kitas; M van der Leeden; S Verberne; H T Jorstad; M Pijnappels; W F Lems; M T Nurmohamed; M van der Esch
Journal:  Clin Rheumatol       Date:  2022-08-25       Impact factor: 3.650

Review 2.  Cardiovascular Disease Risk in Rheumatoid Arthritis Anno 2022.

Authors:  Bas Dijkshoorn; Reinder Raadsen; Michael T Nurmohamed
Journal:  J Clin Med       Date:  2022-05-11       Impact factor: 4.964

3.  Erectile Dysfunction and Cardiovascular Risk in Men With Rheumatoid Arthritis: A Population-based Cohort Study.

Authors:  Katelynn M Wilton; Sara J Achenbach; John M Davis; Elena Myasoedova; Eric L Matteson; Cynthia S Crowson
Journal:  J Rheumatol       Date:  2021-01-15       Impact factor: 5.346

Review 4.  Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout.

Authors:  Romy Hansildaar; Daisy Vedder; Milad Baniaamam; Anne-Kathrin Tausche; Martijn Gerritsen; Michael T Nurmohamed
Journal:  Lancet Rheumatol       Date:  2020-09-01

5.  Use of healthcare resources in a cohort of rheumatoid arthritis patients treated with biological disease-modifying antirheumatic drugs or tofacitinib.

Authors:  Jorge Enrique Machado-Alba; Manuel E Machado-Duque; Andres Gaviria-Mendoza; Juan Manuel Reyes; Natalia Castaño Gamboa
Journal:  Clin Rheumatol       Date:  2020-09-30       Impact factor: 2.980

  5 in total

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