Literature DB >> 31209157

Going After METex14 in NSCLC.

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Abstract

Patients with non-small cell lung cancer harboring MET exon 14 skipping mutations have commonly been treated with the multikinase inhibitor crizotinib, but more MET-specific therapies are being developed. Two such agents, capmatinib and tepotinib, have demonstrated preliminary efficacy in ongoing phase II trials. ©2019 American Association for Cancer Research.

Entities:  

Year:  2019        PMID: 31209157     DOI: 10.1158/2159-8290.CD-ND2019-006

Source DB:  PubMed          Journal:  Cancer Discov        ISSN: 2159-8274            Impact factor:   39.397


  1 in total

1.  Capmatinib in Japanese patients with MET exon 14 skipping-mutated or MET-amplified advanced NSCLC: GEOMETRY mono-1 study.

Authors:  Takashi Seto; Kadoaki Ohashi; Shunichi Sugawara; Makoto Nishio; Masayuki Takeda; Keisuke Aoe; Sanae Moizumi; Satoshi Nomura; Takeshi Tajima; Toyoaki Hida
Journal:  Cancer Sci       Date:  2021-02-24       Impact factor: 6.716

  1 in total

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