Olimpia Castillo Castejón 1 , Inmaculada González 1 , Esther Prieto 1 , Teresa Pérez 1 , Luis E Pablo 1 , Victoria Pueyo 1 Show Affiliations »
Abstract
AIM: To evaluate the relationship between visoperception and anthropometric features related to prenatal alcohol exposure. METHODS: We compared two cohorts of infants aged between 5 and 18 years. Seventy-nine children, adopted from Eastern Europe, were included in the study group. The control group was formed by age and gender matched children born in Spain. All children underwent a full ophthalmologic assessment and standardised testing of visual cognitive skills. RESULTS: Adoptees presented worse visual motor and visual perceptual outcomes in all skills compared with control subjects, with statistically significant difference in test of visual perceptual skills (TVPS) global centile (50.3 vs 66.8; P = 0.001), spatial relationships (64.6 vs 81.9; P = 0.004) and visual figure-ground (52.1 vs 74.1; P = 0.002) tasks. Face recognition was as well significantly worse in adopted children (42.4 vs 57.1; P = 0.009). Twenty-one adopted children (26.6%) had sentinel finding for foetal alcohol spectrum disorders (FASD). Main facial features related to FASD correlated with visual cognitive outcomes. Of the adopted children, those diagnosed of FASD showed incrementally worse visual perceptual and visual motor outcomes (TVPS global centile = 36.86, P = 0.001; TVAS = 10.38, P = 0.002). CONCLUSION: Children adopted from eastern Europe are at increased risk of visual perceptual disabilities, especially those with sentinel findings of foetal alcohol syndrome disorders. ©2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
AIM: To evaluate the relationship between visoperception and anthropometric features related to prenatal alcohol exposure. METHODS: We compared two cohorts of infants aged between 5 and 18 years. Seventy-nine children , adopted from Eastern Europe, were included in the study group. The control group was formed by age and gender matched children born in Spain. All children underwent a full ophthalmologic assessment and standardised testing of visual cognitive skills . RESULTS: Adoptees presented worse visual motor and visual perceptual outcomes in all skills compared with control subjects, with statistically significant difference in test of visual perceptual skills (TVPS) global centile (50.3 vs 66.8; P = 0.001), spatial relationships (64.6 vs 81.9; P = 0.004) and visual figure-ground (52.1 vs 74.1; P = 0.002) tasks. Face recognition was as well significantly worse in adopted children (42.4 vs 57.1; P = 0.009). Twenty-one adopted children (26.6%) had sentinel finding for foetal alcohol spectrum disorders (FASD ). Main facial features related to FASD correlated with visual cognitive outcomes. Of the adopted children , those diagnosed of FASD showed incrementally worse visual perceptual and visual motor outcomes (TVPS global centile = 36.86, P = 0.001; TVAS = 10.38, P = 0.002). CONCLUSION: Children adopted from eastern Europe are at increased risk of visual perceptual disabilities , especially those with sentinel findings of foetal alcohol syndrome disorders . ©2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
Entities: Chemical
Disease
Species
Keywords:
adoption; cognitive impairment; foetal alcohol spectrum disorders; visual perception
Year: 2019
PMID： 31206198 DOI： 10.1111/apa.14904
Source DB: PubMed Journal: Acta Paediatr ISSN： 0803-5253 Impact factor: 2.299