Literature DB >> 31205329

Clinical Pharmacist Impact on Intensive Care Unit Delirium: Intervention and Monitoring.

Myaa Lightfoot1, Adam Sanders1, Christopher Burke1, Jessica Patton1.   

Abstract

Purpose: The purpose of this study was to determine the impact of pharmacist monitoring with a clinical decision support system (CDSS) on clinical outcomes related to intensive care unit (ICU) delirium.
Methods: This was a single-center, before-and-after study. This study compares patient outcomes of the preintervention group, which is the standard of care of pharmacist rounding, and the intervention group of pharmacy rounding with the CDSS rules. Using a CDSS, specific delirium risk factor rules were created to alert pharmacists to patients who have an increased risk of developing ICU delirium. Patients were included in the study if they were ⩾18 years of age, admitted to the trauma intensive care unit (TICU), and had one of the CDSS rule alerts. The CDSS notified pharmacists in real time to patients in the intervention group that met these criteria to provide timely recommendations in an effort to prevent ICU delirium.
Results: Compared with the preintervention group receiving the standard of care (n = 28), the intervention CDSS group (n = 33) had a nonsignificant trend in decreased incidence of delirium (33.3% vs 24.1%, P = .45), ICU length of stay (LOS) (10.11 vs 7.55 days, P = .26), and ventilator duration (7.11 vs 5.03 days, P = .26). The intervention group had a significantly shorter hospital LOS (14.74 vs 9.98 days, P = .04). There was a nonsignificant increase in mortality with the intervention group from nondelirium causes (24.2% vs 7%, P = .07).
Conclusion: The utilization of a CDSS by clinical pharmacists to monitor for delirium-specific risk factors led to a significantly shorter hospital LOS. Further studies using this model are warranted to see the impact on the ICU population.

Entities:  

Keywords:  CDSS; ICU delirium; benzodiazepines; clinical decision support system; delirium; pharmacists; sedation

Year:  2018        PMID: 31205329      PMCID: PMC6535931          DOI: 10.1177/0018578718778226

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


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2.  Early recognition of delirium in trauma patients.

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4.  Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit.

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7.  Delirium and its motoric subtypes: a study of 614 critically ill patients.

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Review 8.  Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit.

Authors:  Juliana Barr; Gilles L Fraser; Kathleen Puntillo; E Wesley Ely; Céline Gélinas; Joseph F Dasta; Judy E Davidson; John W Devlin; John P Kress; Aaron M Joffe; Douglas B Coursin; Daniel L Herr; Avery Tung; Bryce R H Robinson; Dorrie K Fontaine; Michael A Ramsay; Richard R Riker; Curtis N Sessler; Brenda Pun; Yoanna Skrobik; Roman Jaeschke
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Authors:  Timothy D Girard; Pratik P Pandharipande; E Wesley Ely
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