Literature DB >> 31203206

Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services.

Gazala Akram1, Fiona Mitchell2.   

Abstract

Second-generation antipsychotics are used to treat a variety of psychiatric symptoms and illnesses as well as the behavioural aspects of various neurodevelopmental disorders. However, there is reluctance in using second-generation long-acting injectable antipsychotics in child psychiatry services. We present a case of a 12-year-old child whose presentation and medication regime warranted the use of aripiprazole long-acting injection against a backdrop of potential CYP P450 enzyme interactions as a consequence of polypharmacy. The case also describes the difficulties encountered working across different health sectors and agencies and highlights the ongoing need for skills-based Continuous Professional Development for Child and Adolescent Mental Health Services-based nursing staff. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  Child and adolescent psychiatry (paediatrics); Pharmacology and therapeutics; Psychiatry (drugs and medicines)

Mesh:

Substances:

Year:  2019        PMID: 31203206      PMCID: PMC6577303          DOI: 10.1136/bcr-2018-228509

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

Review 1.  Weight gain and metabolic risks associated with antipsychotic medications in children and adolescents.

Authors:  Lawrence Maayan; Christoph U Correll
Journal:  J Child Adolesc Psychopharmacol       Date:  2011-12-13       Impact factor: 2.576

Review 2.  Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders.

Authors:  Christopher J McDougle; Kimberly A Stigler; Craig A Erickson; David J Posey
Journal:  J Clin Psychiatry       Date:  2008       Impact factor: 4.384

3.  Perceptions and knowledge of antipsychotics among mental health professionals and patients.

Authors:  Lindah Cahling; Anders Berntsson; Gabriella Bröms; Lars Öhrmalm
Journal:  BJPsych Bull       Date:  2017-10
  3 in total

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