Literature DB >> 31202324

A pyrazole-containing hydrazone for fluorescent imaging of Al3+ in lysosomes and its resultant Al3+ complex as a sensor for F.

Yuan Wang1, Yu-Fei Song1, Ling Zhang1, Geng-Geng Dai1, Rui-Fang Kang1, Wei-Na Wu2, Zhi-Hong Xu3, Yun-Chang Fan1, Lin-Yan Bian1.   

Abstract

A fluorescence-enhanced and lysosome-targeted Al3+ probe (1) based on a pyrazole-containing hydrazone was developed in this work. The fluorescent probe 1 displays an OFF-ON fluorescence response to Al3+ in the lysosome pH environment. In addition, the resultant 1-Al3+ complex could act as an ON-OFF fluorescence sensor for F-. Fluorescence imaging shows that 1 is suitable for visualization of Al3+ in lysosomes of HeLa cells.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Al(3+); Cell imaging; F(−); Fluorescent probe; Hydrazone; Lysosome

Mesh：

Substances：

Year:  2019        PMID： 31202324     DOI： 10.1016/j.talanta.2019.05.051

Source DB:  PubMed          Journal:  Talanta        ISSN： 0039-9140            Impact factor:   6.057


  2 in total

1.  A sensitive OFF-ON-OFF fluorescent probe for the cascade sensing of Al3+ and F- ions in aqueous media and living cells.

Authors:  Lingjie Hou; Wenting Liang; Chenhua Deng; Caifeng Zhang; Bo Liu; Shaomin Shuang; Yu Wang
Journal:  RSC Adv       Date:  2020-06-05       Impact factor: 4.036

Review 2.  Recent progress in chemosensors based on pyrazole derivatives.

Authors:  Alexis Tigreros; Jaime Portilla
Journal:  RSC Adv       Date:  2020-05-22       Impact factor: 4.036
  2 in total

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