Crevice corrosion - A newly observed mechanism of degradation in biomedical magnesium.

Crevice-induced corrosion is not desirable to occur in metallic magnesium (Mg) during many industrial applications. However, orthopedic implants made of Mg alloys have been demonstrated to degrade faster between the joining surface of bone plates and screws after implantation, suggesting the crevice corrosion may occur in the physiological environment. In this paper, a resin device is designed to parallel high purity magnesium (HP-Mg) plates with closely spaced slits. After a standard corrosion test in the phosphate-buffered saline (PBS) solution, the paralleled HP-Mg samples embedded in the custom-made resin device corrode faster than those without the resin device. The corrosion morphology of Mg with the resin device exhibits features of crevice corrosion with many deep holes and river-like texture. Moreover, implantation of the bone plate and screws in vivo demonstrates similar corrosion morphology as that of the in vitro test, suggesting the occurrence of crevice-enhanced corrosion in the bone-bone plate interface, as well as the contact area between the bone plate and the screws. STATEMENT OF SIGNIFICANCE: Understanding the corrosion behavior of Mg and Mg alloys after implantation is one of the main challenges for developing desirable biodegradable Mg alloys or effective methods to adjust the corrosion rate of Mg-based implants. In this paper, we attempted to understand the corrosion behaviors of HP-Mg at the joining surface between HP-Mg plates or HP-Mg screws and bone tissues after implantation. We designed an in vitro setup to mimic the crevice environment of the in vivo joining surface and found that the crevices existing on the HP-Mg would significantly accelerate the corrosion rate and change the corrosion morphology of HP-Mg plates. The in vivo implantation also showed similar corrosion morphology caused by crevice corrosion, which appeared at the joining surface between HP-Mg plates or HP-Mg screws and bone tissues. Then, we proposed a new corrosion mechanism of Mg-based alloys inside the crevice. The findings of this study can help us broaden our cognition on the corrosion behavior of Mg and Mg alloy-based orthopedic implants.