Damien Eyharts1,2,3, Yoan Lavie-Badie1,2,4,3, Stéphanie Cazalbou1,2,3, Pauline Fournier1,2,3, Eve Cariou1,2,5,3, Pierre Pascal2,4, Francisco Campelo-Parada1,3, Bertrand Marcheix5,3,6, Michel Galinier1,2,5,3, Isabelle Berry2,4,5, Didier Carrié1,2,7,3, Olivier Lairez8,9,10,11,12. 1. Department of Cardiology, Rangueil University Hospital, Toulouse, France. 2. Cardiac Imaging Center, Toulouse University Hospital, Toulouse, France. 3. Heart Valve Center, Toulouse University Hospital, Toulouse, France. 4. Department of Nuclear Medicine, Rangueil University Hospital, Toulouse, France. 5. Medical School of Rangueil, University Paul Sabatier, Toulouse, France. 6. Department of Cardiac Surgery, Rangueil University Hospital, Toulouse, France. 7. Medical School of Purpan, University Paul Sabatier, Toulouse, France. 8. Department of Cardiology, Rangueil University Hospital, Toulouse, France. lairez@gmail.com. 9. Cardiac Imaging Center, Toulouse University Hospital, Toulouse, France. lairez@gmail.com. 10. Department of Nuclear Medicine, Rangueil University Hospital, Toulouse, France. lairez@gmail.com. 11. Medical School of Rangueil, University Paul Sabatier, Toulouse, France. lairez@gmail.com. 12. Heart Valve Center, Toulouse University Hospital, Toulouse, France. lairez@gmail.com.
Abstract
BACKGROUND: Quantitative assessment of valve regurgitation using volumetric method by comparing right and left ventricular stroke volumes is still under investigations. AIMS: To investigate the accuracy of tomographic equilibrium radionuclide ventriculography (t-ERV) for the quantification of tricuspid regurgitation (TR). METHODS AND RESULTS: Sixty-one patients (44 men; mean age 59 ± 12 years) who underwent both t-ERV and transthoracic echocardiography (TTE) studies within 2 weeks for right ventricular systolic function assessment were eligible for inclusion. A sub-group of 22 patients underwent both t-ERV and CMR. Patients with mitral/aortic regurgitation by TTE were excluded of the study. TR regurgitant volume (RVol) was calculated using the proximal isovelocity surface area (PISA) method from TTE and the volumetric method (right ventricular stroke volume minus left ventricular stroke volume) from t-ERV. There was a significant correlation between RVol as assess by ERV and by TTE (R = 0.95, P < 0.0001). Intraclass correlation coefficient between TTE and ERV for TR quantification was 0.95 (P < 0.0001). Among patients who underwent CMR, the correlation between RVol obtained by TTE and by t-ERV and CMR were R = 0.81 and R = 0.75, respectively (all P < 0.0001). CONCLUSION: TR assessment using the t-ERV correlates well with PISA from TTE in patients referred for right ventricular systolic function assessment.
BACKGROUND: Quantitative assessment of valve regurgitation using volumetric method by comparing right and left ventricular stroke volumes is still under investigations. AIMS: To investigate the accuracy of tomographic equilibrium radionuclide ventriculography (t-ERV) for the quantification of tricuspid regurgitation (TR). METHODS AND RESULTS: Sixty-one patients (44 men; mean age 59 ± 12 years) who underwent both t-ERV and transthoracic echocardiography (TTE) studies within 2 weeks for right ventricular systolic function assessment were eligible for inclusion. A sub-group of 22 patients underwent both t-ERV and CMR. Patients with mitral/aortic regurgitation by TTE were excluded of the study. TR regurgitant volume (RVol) was calculated using the proximal isovelocity surface area (PISA) method from TTE and the volumetric method (right ventricular stroke volume minus left ventricular stroke volume) from t-ERV. There was a significant correlation between RVol as assess by ERV and by TTE (R = 0.95, P < 0.0001). Intraclass correlation coefficient between TTE and ERV for TR quantification was 0.95 (P < 0.0001). Among patients who underwent CMR, the correlation between RVol obtained by TTE and by t-ERV and CMR were R = 0.81 and R = 0.75, respectively (all P < 0.0001). CONCLUSION: TR assessment using the t-ERV correlates well with PISA from TTE in patients referred for right ventricular systolic function assessment.