Kazunori Ninomiya1, Shuji Toya2, Ichiro Ogura3. 1. Comprehensive Dental Care, The Nippon Dental University Niigata Hospital, Niigata, Japan. 2. Oral and Maxillofacial Surgery, Dry Mouth Clinic, The Nippon Dental University Niigata Hospital, Niigata, Japan. 3. Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, 1-8 Hamaura-cho, Chuo-ku, Niigata, 951-8580, Niigata, Japan. ogura@ngt.ndu.ac.jp.
Abstract
OBJECTIVES: The aim of this study was to investigate of salivary gland dysfunction with single-photon emission computed tomography/computed tomography (SPECT/CT), especially the relationship between maximum standardized uptake value (SUVmax) of salivary glands and their dysfunction. METHODS: Five patients (2 submandibular sialolithiasis, 2 Sjögren's syndrome, and 1 parotitis) who underwent SPECT/CT were included in this study. The salivary gland excretion function was defined as A (pre-stimulatory 20 min after injection of Tc-99m pertechnetate)/B (post-stimulatory 40 min after injection of Tc-99m pertechnetate) using SUVmax of parotid and submandibular glands. RESULTS: SUVmax before stimulation of the submandibular gland with sialoliths in a patient was lower than that in the opposite submandibular gland without sialoliths (5.81 vs 51.37). Furthermore, the A/B using SUVmax in the other patient of submandibular glands with sialoliths was lower than that in the opposite submandibular glands without sialoliths (0.70 vs 1.85). The A/B using SUVmax of right and left parotid gland in a patient with Sjögren's syndrome was 1.06 and 0.74, respectively. Furthermore, the A/B using SUVmax of right and left parotid glands in the other patient with Sjögren's syndrome was 3.20 and 4.32, respectively. The A/B using SUVmax of right and left parotid glands in a patient with left parotitis was 2.26 and 1.58, respectively. CONCLUSION: The results of the present study indicate that SUVmax using SPECT/CT seems a useful tool for evaluation of the salivary gland dysfunction.
OBJECTIVES: The aim of this study was to investigate of salivary gland dysfunction with single-photon emission computed tomography/computed tomography (SPECT/CT), especially the relationship between maximum standardized uptake value (SUVmax) of salivary glands and their dysfunction. METHODS: Five patients (2 submandibular sialolithiasis, 2 Sjögren's syndrome, and 1 parotitis) who underwent SPECT/CT were included in this study. The salivary gland excretion function was defined as A (pre-stimulatory 20 min after injection of Tc-99m pertechnetate)/B (post-stimulatory 40 min after injection of Tc-99m pertechnetate) using SUVmax of parotid and submandibular glands. RESULTS: SUVmax before stimulation of the submandibular gland with sialoliths in a patient was lower than that in the opposite submandibular gland without sialoliths (5.81 vs 51.37). Furthermore, the A/B using SUVmax in the other patient of submandibular glands with sialoliths was lower than that in the opposite submandibular glands without sialoliths (0.70 vs 1.85). The A/B using SUVmax of right and left parotid gland in a patient with Sjögren's syndrome was 1.06 and 0.74, respectively. Furthermore, the A/B using SUVmax of right and left parotid glands in the other patient with Sjögren's syndrome was 3.20 and 4.32, respectively. The A/B using SUVmax of right and left parotid glands in a patient with left parotitis was 2.26 and 1.58, respectively. CONCLUSION: The results of the present study indicate that SUVmax using SPECT/CT seems a useful tool for evaluation of the salivary gland dysfunction.