Literature DB >> 31201631

The Generation of the Human mAb RabD4 Specific to the Rabies Virus Glycoprotein and Characterization Thereof.

E N Ilina1, E V Solopova2, T K Aliev3, M V Larina4, D S Balabashin4, N E Varlamov2, D A Dolgikh3,4, P G Sveshnikov2, M P Kirpichnikov3,4.   

Abstract

We generated a novel human neutralizing human mAb RabD4 against rabies virus glycoprotein using in vitro stimulation of human peripheral B cells produced by immunized donor. The human mAb RabD4 showed a high antigen-binding activity and virus-neutralizing activity in the FAVN test with the CVS-11 rabies virus.

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Year:  2019        PMID： 31201631     DOI： 10.1134/S1607672919020133

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  4 in total

1.  Continuous cultures of fused cells secreting antibody of predefined specificity.

Authors:  G Köhler; C Milstein
Journal:  Nature       Date:  1975-08-07       Impact factor: 49.962

Review 2.  A human monoclonal antibody cocktail as a novel component of rabies postexposure prophylaxis.

Authors:  John de Kruif; Alexander B H Bakker; Wilfred E Marissen; R Arjen Kramer; Mark Throsby; Charles E Rupprecht; Jaap Goudsmit
Journal:  Annu Rev Med       Date:  2007       Impact factor: 13.739

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

Review 4.  The spread and evolution of rabies virus: conquering new frontiers.

Authors:  Christine R Fisher; Daniel G Streicker; Matthias J Schnell
Journal:  Nat Rev Microbiol       Date:  2018-02-26       Impact factor: 60.633
  4 in total

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