Literature DB >> 31201624

Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain.

A A Mozhaev1,2, A N Orsa3, I E Deyev3, V I Shvets4, A G Petrenko3.   

Abstract

In this paper, we present an approach to optimize the heterologous expression of the receptor tyrosine kinase IRR, which further simplifies the purification of the IRR from the medium and increases the final yield. The approach proposed by us can find application in the biotechnological production of other large-scale recombinant proteins produced for medical purposes.

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Year:  2019        PMID: 31201624     DOI: 10.1134/S1607672919020017

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN: 1607-6729            Impact factor:   0.788


  11 in total

1.  Structure of the insulin receptor ectodomain reveals a folded-over conformation.

Authors:  Neil M McKern; Michael C Lawrence; Victor A Streltsov; Mei-Zhen Lou; Timothy E Adams; George O Lovrecz; Thomas C Elleman; Kim M Richards; John D Bentley; Patricia A Pilling; Peter A Hoyne; Kellie A Cartledge; Tam M Pham; Jennifer L Lewis; Sonia E Sankovich; Violet Stoichevska; Elizabeth Da Silva; Christine P Robinson; Maurice J Frenkel; Lindsay G Sparrow; Ross T Fernley; V Chandana Epa; Colin W Ward
Journal:  Nature       Date:  2006-09-06       Impact factor: 49.962

2.  Regulation of CIRL-1 proteolysis and trafficking.

Authors:  Igor E Deyev; Alexander G Petrenko
Journal:  Biochimie       Date:  2010-01-25       Impact factor: 4.079

3.  Structural determinants of the insulin receptor-related receptor activation by alkali.

Authors:  Igor E Deyev; Alla V Mitrofanova; Egor S Zhevlenev; Nikita Radionov; Anastasiya A Berchatova; Nadezhda V Popova; Oxana V Serova; Alexander G Petrenko
Journal:  J Biol Chem       Date:  2013-10-11       Impact factor: 5.157

4.  Insulin receptor-related receptor as an extracellular alkali sensor.

Authors:  Igor E Deyev; Fabien Sohet; Konstantin P Vassilenko; Oxana V Serova; Nadezhda V Popova; Sergey A Zozulya; Elena B Burova; Pascal Houillier; Dmitry I Rzhevsky; Anastasiya A Berchatova; Arkady N Murashev; Anton O Chugunov; Roman G Efremov; Nikolai N Nikol'sky; Eugenio Bertelli; Dominique Eladari; Alexander G Petrenko
Journal:  Cell Metab       Date:  2011-06-08       Impact factor: 27.287

5.  Mapping of alkali-sensing sites of the insulin receptor-related receptor. The role of L2 and fibronectin domains.

Authors:  Igor E Deyev; Natalia A Chachina; Dinara M Shayahmetova; Oxana V Serova; Alexander G Petrenko
Journal:  Biochimie       Date:  2015-01-15       Impact factor: 4.079

6.  Alkaline pH induces IRR-mediated phosphorylation of IRS-1 and actin cytoskeleton remodeling in a pancreatic beta cell line.

Authors:  Igor E Deyev; Nadezhda V Popova; Oxana V Serova; Svetlana V Zhenilo; Marì Regoli; Eugenio Bertelli; Alexander G Petrenko
Journal:  Biochimie       Date:  2017-04-22       Impact factor: 4.079

Review 7.  Insulin receptor-related receptor as an extracellular pH sensor involved in the regulation of acid-base balance.

Authors:  Alexander G Petrenko; Sergey A Zozulya; Igor E Deyev; Dominique Eladari
Journal:  Biochim Biophys Acta       Date:  2012-12-07

8.  How insulin engages its primary binding site on the insulin receptor.

Authors:  John G Menting; Jonathan Whittaker; Mai B Margetts; Linda J Whittaker; Geoffrey K-W Kong; Brian J Smith; Christopher J Watson; Lenka Záková; Emília Kletvíková; Jiří Jiráček; Shu Jin Chan; Donald F Steiner; Guy G Dodson; Andrzej M Brzozowski; Michael A Weiss; Colin W Ward; Michael C Lawrence
Journal:  Nature       Date:  2013-01-10       Impact factor: 49.962

9.  Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis.

Authors:  Valery Krasnoperov; Igor E Deyev; Oxana V Serova; Chongfeng Xu; Yun Lu; Leonid Buryanovsky; Alexander G Gabibov; Thomas A Neubert; Alexander G Petrenko
Journal:  Biochemistry       Date:  2009-04-14       Impact factor: 3.162

10.  Determination of Alkali-Sensing Parts of the Insulin Receptor-Related Receptor Using the Bioinformatic Approach.

Authors:  I E Deyev; N V Popova; A G Petrenko
Journal:  Acta Naturae       Date:  2015 Apr-Jun       Impact factor: 1.845

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