Literature DB >> 31199910

Could iPSCs Enable "Off-the-Shelf" Cell Therapy?

Diana Crow1.   

Abstract

An "off-the-shelf" cell therapy derived from induced pluripotent stem cells (iPSCs) has entered clinical trials in the United States. Other companies are following suit, harnessing iPSCs' self-renewal ability to manufacture cell therapies that don't require customization for each patient. But some experts aren't sure such therapies are a good idea.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31199910     DOI: 10.1016/j.cell.2019.05.043

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  3 in total

Review 1.  Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients' Brain in a Dish.

Authors:  Suleva Povea-Cabello; Marina Villanueva-Paz; Juan M Suárez-Rivero; Mónica Álvarez-Córdoba; Irene Villalón-García; Marta Talaverón-Rey; Alejandra Suárez-Carrillo; Manuel Munuera-Cabeza; José A Sánchez-Alcázar
Journal:  Front Genet       Date:  2021-01-12       Impact factor: 4.599

2.  Modeling MyD88 Deficiency In Vitro Provides New Insights in Its Function.

Authors:  Nils Craig-Mueller; Ruba Hammad; Roland Elling; Jamal Alzubi; Barbara Timm; Julia Kolter; Nele Knelangen; Christien Bednarski; Birgitta Gläser; Sandra Ammann; Zoltán Ivics; Judith Fischer; Carsten Speckmann; Klaus Schwarz; Nico Lachmann; Stephan Ehl; Thomas Moritz; Philipp Henneke; Toni Cathomen
Journal:  Front Immunol       Date:  2020-12-23       Impact factor: 7.561

3.  Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts.

Authors:  Sami Jalil; Timo Keskinen; Rocío Maldonado; Joonas Sokka; Ras Trokovic; Timo Otonkoski; Kirmo Wartiovaara
Journal:  Stem Cell Reports       Date:  2021-11-24       Impact factor: 7.765

  3 in total

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