| Literature DB >> 31199154 |
Kang-Sheng Zhou1, Ping Yi2, Tao Yang3, Wen Tian1, Fu-Mei Yang2, Kuo-Hsiung Lee4,5, Bao-Yu Zhao6, Yue-Hu Wang3, Cheng-Jian Tan1.
Abstract
Ochrocephalamines B-D (1-3), composed of fused quinolizidine and octahydroquinoline rings, were isolated from Oxytropis ochrocephala Bunge. Ochrocephalamine B (1) has a unique bridged tetracyclic ring skeleton fused with a lactam ring. The structures of 1-3 were elucidated using spectroscopic and computational approaches. Ochrocephalamine C (2) and D (3) demonstrated potent anti-HBV activities and are more potent against the secretion of HBeAg than that of HBsAg.Entities:
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Year: 2019 PMID： 31199154 DOI： 10.1021/acs.orglett.9b01643
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005