Chaohua Li1, Jose N Binongo2, Vijaya Kancherla3. 1. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, 30322, USA. Chaohua.li@alumni.emory.edu. 2. Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, 30322, USA. 3. Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, 30322, USA.
Abstract
OBJECTIVES: Pregnancy-associated hypertension (PAH) includes gestational hypertension, preeclampsia and eclampsia. Although a protective effect of multi-parity on PAH has been reported in previous studies, the association has not been examined among Asian American women in the U.S. METHODS: Using data from 2014 U.S. National Vital Statistics System, we examined the prevalence of PAH among Asian American women who had singleton live births (N = 235,303), and its association with parity (number of previous pregnancies including live births and fetal deaths) controlling for potential confounders. We estimated adjusted odds ratios (aORs) and 95% confidence intervals (CI) using multivariable logistic regression analysis. RESULTS: Overall, 2.72% (95% CI 2.66%, 2.79%) of Asian American women were recorded to have PAH during pregnancy. Parity was inversely associated with PAH in our study, where Asian American women who had 1-2 and 3 or more previous pregnancies had significantly lower odds of PAH (aOR 0.61, 95% CI 0.58, 0.65; and aOR 0.62, 95% CI 0.57, 0.68, respectively) compared to nulliparous women, after controlling for potential confounders. CONCLUSIONS: Recent U.S. vital statistics data revealed that nulliparity is significantly associated with PAH among Asian American women. Future studies should identify specific factors that are associated with PAH and factors contributing to disparities in PAH risk among Asian American women.
OBJECTIVES: Pregnancy-associated hypertension (PAH) includes gestational hypertension, preeclampsia and eclampsia. Although a protective effect of multi-parity on PAH has been reported in previous studies, the association has not been examined among Asian American women in the U.S. METHODS: Using data from 2014 U.S. National Vital Statistics System, we examined the prevalence of PAH among Asian American women who had singleton live births (N = 235,303), and its association with parity (number of previous pregnancies including live births and fetal deaths) controlling for potential confounders. We estimated adjusted odds ratios (aORs) and 95% confidence intervals (CI) using multivariable logistic regression analysis. RESULTS: Overall, 2.72% (95% CI 2.66%, 2.79%) of Asian American women were recorded to have PAH during pregnancy. Parity was inversely associated with PAH in our study, where Asian American women who had 1-2 and 3 or more previous pregnancies had significantly lower odds of PAH (aOR 0.61, 95% CI 0.58, 0.65; and aOR 0.62, 95% CI 0.57, 0.68, respectively) compared to nulliparous women, after controlling for potential confounders. CONCLUSIONS: Recent U.S. vital statistics data revealed that nulliparity is significantly associated with PAH among Asian American women. Future studies should identify specific factors that are associated with PAH and factors contributing to disparities in PAH risk among Asian American women.
Entities:
Keywords:
Asian American; Maternal health; Parity; Pregnancy-associated hypertension; Risk factors
Authors: Erica P Gunderson; Vicky Chiang; Cora E Lewis; Janet Catov; Charles P Quesenberry; Stephen Sidney; Gina S Wei; Roberta Ness Journal: Obstet Gynecol Date: 2008-12 Impact factor: 7.661
Authors: X Q Lao; G N Thomas; C Q Jiang; W S Zhang; P Yin; M Schooling; M Heys; G M Leung; P Adab; K K Cheng; T H Lam Journal: Clin Endocrinol (Oxf) Date: 2006-10 Impact factor: 3.478
Authors: Hawawu Hussein; Mansour Shamsipour; Masud Yunesian; Mohammad Sadegh Hassanvand; Abraham Assan; Akbar Fotouhi Journal: Iran J Public Health Date: 2021-06 Impact factor: 1.429