Literature DB >> 31194251

Potential Clinical Effects of a Novel Rapid Diagnostic Panel for Pediatric Musculoskeletal Infections.

Justin B Searns1,2, Jane Gralla3, Sarah K Parker2, Samuel R Dominguez2.   

Abstract

A direct-from-source rapid musculoskeletal diagnostic panel (MDP) was validated recently. We compared clinical measures to theoretical time points had MDP results been available. The MDP would have significantly decreased the time to pathogen identification (7 hours), time to definitive antimicrobial therapy (22 hours), and hospital length of stay (26.4 hours).
© The Author(s) 2019. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  diagnostics; infection; osteomyelitis; pediatric; septic arthritis

Mesh：

Substances：

Year:  2020        PMID： 31194251      PMCID： PMC7358044          DOI： 10.1093/jpids/piz040

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN： 2048-7193            Impact factor:   3.164


  7 in total

1.  Acute osteomyelitis in children: a population-based retrospective study 1965 to 1994.

Authors:  L B Dahl; A L Høyland; H Dramsdahl; P I Kaaresen
Journal:  Scand J Infect Dis       Date:  1998

2.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

3.  Changing patterns of acute hematogenous osteomyelitis and septic arthritis: emergence of community-associated methicillin-resistant Staphylococcus aureus.

Authors:  Sandra R Arnold; David Elias; Steven C Buckingham; Eddie D Thomas; Eduardo Novais; Alexandre Arkader; Cassandra Howard
Journal:  J Pediatr Orthop       Date:  2006 Nov-Dec       Impact factor: 2.324

Review 4.  Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment.

Authors:  Shawn S Funk; Lawson A B Copley
Journal:  Orthop Clin North Am       Date:  2017-04       Impact factor: 2.472

5.  Validation of a novel molecular diagnostic panel for pediatric musculoskeletal infections: Integration of the Cepheid Xpert MRSA/SA SSTI and laboratory-developed real-time PCR assays for clindamycin resistance genes and Kingella kingae detection.

Authors:  Justin B Searns; Christine C Robinson; Qi Wei; Ji Yuan; Stacey Hamilton; Kristin Pretty; Nathan Donaldson; Sarah K Parker; Samuel R Dominguez
Journal:  J Microbiol Methods       Date:  2018-12-07       Impact factor: 2.363

6.  The impact of the current epidemiology of pediatric musculoskeletal infection on evaluation and treatment guidelines.

Authors:  Omar A Gafur; Lawson A B Copley; S Tyler Hollmig; Richard H Browne; Lori A Thornton; Shellye E Crawford
Journal:  J Pediatr Orthop       Date:  2008 Oct-Nov       Impact factor: 2.324

7.  Clinical Care Guideline for Improving Pediatric Acute Musculoskeletal Infection Outcomes.

Authors:  Murray D Spruiell; Justin Benjamin Searns; Travis C Heare; Jesse L Roberts; Erin Wylie; Laura Pyle; Nathan Donaldson; Jaime R Stewart; Heather Heizer; Jennifer Reese; Halden F Scott; Kelly Pearce; Colin J Anderson; Mark Erickson; Sarah K Parker
Journal:  J Pediatric Infect Dis Soc       Date:  2017-09-01       Impact factor: 3.164
  7 in total
  1 in total

1.  Use of Metagenomic Next-Generation Sequencing to Identify Pathogens in Pediatric Osteoarticular Infections.

Authors:  Nanda Ramchandar; Jessica Burns; Nicole G Coufal; Andrew Pennock; Benjamin Briggs; Rita Stinnett; John Bradley; John Arnold; George Y Liu; Maya Pring; Vidyadhar V Upasani; Kathleen Rickert; David Dimmock; Charles Chiu; Lauge Farnaes; Christopher Cannavino
Journal:  Open Forum Infect Dis       Date:  2021-07-17       Impact factor: 3.835
  1 in total

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