Literature DB >> 31191694

Comparative evaluation of clinical efficiency of intramuscular diazepam-ketamine, medetomidine-ketamine, and xylazine-ketamine anaesthesia in Ring-necked pheasants (Phasianus colchicus).

M Kaya1, H O Nisbet2, M Cenesiz1.   

Abstract

BACKGROUND: Several injectable anaesthetics and sedatives are used in various avian species for general anaesthesia. Birds are very sensitive animals and any mismanagement in a crisis can lead to immediate shock and death. Therefore, careful selection of the safest possible anaesthetic agent and dose is very important. AIMS: The aim of this study was to examine the clinical efficiency of diazepam-ketamine (DK), medetomidine-ketamine (MK), and xylazine-ketamine (XK) combinations anaesthetic regimens in pheasants.
METHODS: Twenty-four pheasants were divided into three equal groups and received one of three anaesthetic combinations by intramuscular injections: 9.0 mg/kg diazepam and 150.0 mg/kg ketamine, 0.20 mg/kg medetomidine and 80.0 mg/kg ketamine, and 3.0 mg/kg xylazine and 80.0 mg/kg ketamine. Each pheasant was pre-medicated with sedative drugs and 5 min later, anaesthesia was induced with ketamine injection.
RESULTS: The weak time (2.50 ± 1.07 min; mean±SD) and down time (6.13 ± 1.25 min) were shortest in group XK. The sleep time was longest (73 ± 20.24 min) while the recovery time (157 ± 13.61 min) was shortest in group MK. Muscle relaxation was excellent during the anaesthesia in all groups. The recovery phase of the birds was uneventful. Heart rate (HR) in DK group was statistically higher than MK and XK groups. Body temperature (BT) decreased in all groups compared to baseline values and those of MK group were lower than DK and XK groups. Respiratory rate (RR) in XK group was significantly lower than DK and MK groups.
CONCLUSION: In conclusion, the MK combination shows better anaesthetic outcome compared to DK or XK combinations in pheasants.

Entities:  

Keywords:  Diazepam; Ketamine; Medetomidine; Pheasant; Xylazine

Year:  2019        PMID: 31191694      PMCID: PMC6509906     

Source DB:  PubMed          Journal:  Iran J Vet Res        ISSN: 2252-0589            Impact factor:   1.376


  11 in total

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Authors:  Jack Varner; Kelli R Clifton; Stacy Poulos; J Roger Broderson; Roger D Wyatt
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Authors:  Giuliano Q Mostachio; Luciana D de-Oliveira; Aulus C Carciofi; Wilter R R Vicente
Journal:  Vet Anaesth Analg       Date:  2008-02-18       Impact factor: 1.648

4.  Cardiovascular, respiratory, thermoregulatory, sedative, and analgesic effects of intravenous administration of medetomidine in rhesus macaques (Macaca mulatta).

Authors:  S V Capuano; N W Lerche; C R Valverde
Journal:  Lab Anim Sci       Date:  1999-10

5.  Xylazine, diazepam and midazolam premedicated ketamine anaesthesia in white Leghorn cockerels for typhlectomy.

Authors:  S K Maiti; R Tiwary; P Vasan; A Dutta
Journal:  J S Afr Vet Assoc       Date:  2006-03       Impact factor: 1.474

Review 6.  Ketamine use: a review.

Authors:  Celia J A Morgan; H Valerie Curran
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7.  Effect of medetomidine-butorphanol-ketamine anaesthesia and atipamezole on heart and respiratory rate and cloacal temperature of domestic pigeons.

Authors:  G Atalan; M Uzun; I Demirkan; S Yildiz; M Cenesiz
Journal:  J Vet Med A Physiol Pathol Clin Med       Date:  2002-08

Review 8.  A review of the physiological effects of alpha2-agonists related to the clinical use of medetomidine in small animal practice.

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Journal:  Can Vet J       Date:  2003-11       Impact factor: 1.008

9.  Dose-response anesthetic effects of ketamine in the chicken.

Authors:  C J McGrath; J C Lee; V L Campbell
Journal:  Am J Vet Res       Date:  1984-03       Impact factor: 1.156

10.  Comparison of various anesthetic regimens in the domestic fowl.

Authors:  J Christensen; R T Fosse; O J Halvorsen; I Morild
Journal:  Am J Vet Res       Date:  1987-11       Impact factor: 1.156

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