| Literature DB >> 311914 |
W Z Catterton, M B Escobedo, W R Sexson, M E Gray, H W Sundell, M T Stahlman.
Abstract
Injection of epidermal growth factor (EGF) into 24-day rabbit fetuses (5 microgram, im or ip) induced accelerated maturation of the lung. On sacrifice at day 27, there was greater distensibility and stability on deflation associated with the appearance of a complement of type II cells approaching that of the rabbit at term. EGF treatment had no demonstrable effect on body weight or lung weight in this group of animals. Saline-injected control fetuses were not affected significantly.Entities:
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Year: 1979 PMID: 311914 DOI: 10.1203/00006450-197902000-00004
Source DB: PubMed Journal: Pediatr Res ISSN: 0031-3998 Impact factor: 3.756