M Pattamatta1,2, B J J Smeets2,3, S M A A Evers1,4, E G Peters2,5, M D P Luyer2, M Hiligsmann1. 1. Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands. 2. Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands. 3. GROW school of oncology and developmental biology, Maastricht University, Maastricht, The Netherlands. 4. Center for Economic Evaluations, Trimbos Institute of Mental Health and Addiction, Utrecht, The Netherlands. 5. Tytgat Institute of Liver and Intestinal Research, University of Amsterdam, Amsterdam, The Netherlands.
Abstract
Objective: To assess the quality of life and societal costs of patients prior to colorectal surgery in the Netherlands. Methods: This study is embedded in a previous randomized controlled trial (SANICS II). The quality of life was measured using EQ-5D-5L questionnaires. The iMTA medical consumption questionnaire (iMCQ) and the iMTA productivity costs questionnaire (iPCQ) were used to identify and measure healthcare and productivity costs. Subgroup analyses were performed based on age and gender. Results:A total of 178 patients were included in the cost analysis and a total of 161 patients in the quality of life analysis. The three-month mean societal cost per patient amounted to €3,211 of which €1,459 was due to productivity losses. The mean utility was 0.88 per patient. Gender was an important predictor in quality of life with men scoring significantly higher than women (0.92 versus 0.82) at p < 0.0001. Conclusion: Colorectal cancer represents a high economic burden in the Netherlands. Further research with repeated cost and quality of life measurements would be needed to explore the change over time and the effects of surgery.
RCT Entities:
Objective: To assess the quality of life and societal costs of patients prior to colorectal surgery in the Netherlands. Methods: This study is embedded in a previous randomized controlled trial (SANICS II). The quality of life was measured using EQ-5D-5L questionnaires. The iMTA medical consumption questionnaire (iMCQ) and the iMTA productivity costs questionnaire (iPCQ) were used to identify and measure healthcare and productivity costs. Subgroup analyses were performed based on age and gender. Results: A total of 178 patients were included in the cost analysis and a total of 161 patients in the quality of life analysis. The three-month mean societal cost per patient amounted to €3,211 of which €1,459 was due to productivity losses. The mean utility was 0.88 per patient. Gender was an important predictor in quality of life with men scoring significantly higher than women (0.92 versus 0.82) at p < 0.0001. Conclusion:Colorectal cancer represents a high economic burden in the Netherlands. Further research with repeated cost and quality of life measurements would be needed to explore the change over time and the effects of surgery.
Entities:
Keywords:
Colorectal cancer; Netherlands; costs; quality of life
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