Jintao Guo1, Bowen Duan1, Siyu Sun2, Sheng Wang1, Xiang Liu1, Nan Ge1, Wen Liu1, Shupeng Wang1, Jinlong Hu1. 1. Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning, China. 2. Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning, China. sun-siyu@163.com.
Abstract
BACKGROUND AND AIMS: Endoscopic ultrasound (EUS)-guided drainage has become the treatment of choice for walled-off pancreatic necrosis (WOPN). However, no consensus exists on the most significant patient- and procedure-related factors that affect prognosis. The aim of the study is to investigate the correlation between patient- and procedure-related factors and post-procedure complications after EUS-guided drainage. METHODS: A retrospective analysis of the clinical characteristics of patients with WOPN who underwent EUS-guided drainage at our endoscopy center between November 2011 and August 2017 was performed. Chi-square analysis and binary logistic regression statistical methods were used to analyze the correlation between influencing factors and prognosis. RESULTS: A total of 85 patients (male/female, 50/35) with WOPN were included in the study. The average age was 44.95 years. The cyst diameter was 10.58 ± 4.78 cm. Multivariate analysis showed that WOPN with higher solid content (> 30%) increased the probability of endoscopic necrosectomy (OR 6.798; 95% CI 1.423, 32.470; p = 0.016). The use of a metal stent increased the probability of endoscopic necrosectomy (OR 3.503; 95% CI 1.251, 9.810; p = 0.017) and the length of hospitalization (OR 3.315; 95% CI 1.192, 9.215; p = 0.022). Female patients had a higher probability of requiring endoscopic necrosectomy (OR 2.683; 95% CI 1.027, 7.007; p = 0.044) and prolonged hospitalization (OR 2.675; 95% CI 1.065, 6.721; p = 0.036). CONCLUSION: The solid content of WOPN, type of stent, and sex of patients were associated with increased probability of endoscopic necrosectomy.
BACKGROUND AND AIMS: Endoscopic ultrasound (EUS)-guided drainage has become the treatment of choice for walled-off pancreatic necrosis (WOPN). However, no consensus exists on the most significant patient- and procedure-related factors that affect prognosis. The aim of the study is to investigate the correlation between patient- and procedure-related factors and post-procedure complications after EUS-guided drainage. METHODS: A retrospective analysis of the clinical characteristics of patients with WOPN who underwent EUS-guided drainage at our endoscopy center between November 2011 and August 2017 was performed. Chi-square analysis and binary logistic regression statistical methods were used to analyze the correlation between influencing factors and prognosis. RESULTS: A total of 85 patients (male/female, 50/35) with WOPN were included in the study. The average age was 44.95 years. The cyst diameter was 10.58 ± 4.78 cm. Multivariate analysis showed that WOPN with higher solid content (> 30%) increased the probability of endoscopic necrosectomy (OR 6.798; 95% CI 1.423, 32.470; p = 0.016). The use of a metal stent increased the probability of endoscopic necrosectomy (OR 3.503; 95% CI 1.251, 9.810; p = 0.017) and the length of hospitalization (OR 3.315; 95% CI 1.192, 9.215; p = 0.022). Female patients had a higher probability of requiring endoscopic necrosectomy (OR 2.683; 95% CI 1.027, 7.007; p = 0.044) and prolonged hospitalization (OR 2.675; 95% CI 1.065, 6.721; p = 0.036). CONCLUSION: The solid content of WOPN, type of stent, and sex of patients were associated with increased probability of endoscopic necrosectomy.
Authors: V Raman Muthusamy; Vinay Chandrasekhara; Ruben D Acosta; David H Bruining; Krishnavel V Chathadi; Mohamad A Eloubeidi; Ashley L Faulx; Lisa Fonkalsrud; Suryakanth R Gurudu; Mouen A Khashab; Shivangi Kothari; Jenifer R Lightdale; Shabana F Pasha; John R Saltzman; Aasma Shaukat; Amy Wang; Julie Yang; Brooks D Cash; John M DeWitt Journal: Gastrointest Endosc Date: 2016-01-13 Impact factor: 9.427
Authors: Gabriel D Lang; Cassandra Fritz; Trisha Bhat; Koushik K Das; Faris M Murad; Dayna S Early; Steven A Edmundowicz; Vladimir M Kushnir; Daniel K Mullady Journal: Gastrointest Endosc Date: 2017-07-14 Impact factor: 9.427
Authors: Timothy B Gardner; Nayantara Coelho-Prabhu; Stuart R Gordon; Andres Gelrud; John T Maple; Georgios I Papachristou; Martin L Freeman; Mark D Topazian; Rajeev Attam; Todd A Mackenzie; Todd H Baron Journal: Gastrointest Endosc Date: 2011-01-14 Impact factor: 9.427
Authors: Olaf J Bakker; Hjalmar C van Santvoort; Sandra van Brunschot; Ronald B Geskus; Marc G Besselink; Thomas L Bollen; Casper H van Eijck; Paul Fockens; Eric J Hazebroek; Rian M Nijmeijer; Jan-Werner Poley; Bert van Ramshorst; Frank P Vleggaar; Marja A Boermeester; Hein G Gooszen; Bas L Weusten; Robin Timmer Journal: JAMA Date: 2012-03-14 Impact factor: 56.272
Authors: Reem Z Sharaiha; Amy Tyberg; Mouen A Khashab; Nikhil A Kumta; Kunal Karia; Jose Nieto; Uzma D Siddiqui; Irving Waxman; Virendra Joshi; Petros C Benias; Peter Darwin; Christopher J DiMaio; Christopher J Mulder; Shai Friedland; David G Forcione; Divyesh V Sejpal; Tamas A Gonda; Frank G Gress; Monica Gaidhane; Ann Koons; Ersilia M DeFilippis; Sanjay Salgado; Kristen R Weaver; John M Poneros; Amrita Sethi; Sammy Ho; Vivek Kumbhari; Vikesh K Singh; Alan H Tieu; Viviana Parra; Alisa Likhitsup; Craig Womeldorph; Brenna Casey; Sreeni S Jonnalagadda; Amit P Desai; David L Carr-Locke; Michel Kahaleh; Ali A Siddiqui Journal: Clin Gastroenterol Hepatol Date: 2016-05-14 Impact factor: 11.382
Authors: Yen-I Chen; Alan N Barkun; Viviane Adam; Ge Bai; Vikesh K Singh; Majidah Bukhari; Olaya Brewer Gutierrez; B Joseph Elmunzer; Robert Moran; Lea Fayad; Mohamad El Zein; Vivek Kumbhari; Alessandro Repici; Mouen A Khashab Journal: Gastrointest Endosc Date: 2018-04-01 Impact factor: 9.427
Authors: Linda Yan; Andrew Dargan; Jose Nieto; Reem Z Shariaha; Kenneth F Binmoeller; Douglas G Adler; Michael DeSimone; Tyler Berzin; Mandeep Swahney; Peter V Draganov; Dennis J Yang; David L Diehl; Lillian Wang; Asma Ghulab; Nausharwan Butt; Ali A Siddiqui Journal: Endosc Ultrasound Date: 2019 May-Jun Impact factor: 5.628
Authors: Laura González-González; Sergio Bazaga; Marianette Murzi; Anna Brujats; Mireia Trias; Beatriz de Riba; Raffaella Romito; Juan Colán-Hernández; Mar Concepción; Jordi Gordillo; Juan Carlos Pernas; Maria Poca; German Soriano; Carlos Guarner-Argente Journal: Surg Endosc Date: 2021-03-03 Impact factor: 4.584
Authors: Ali Ramouz; Saeed Shafiei; Sadeq Ali-Hasan-Al-Saegh; Elias Khajeh; Ricardo Rio-Tinto; Sanam Fakour; Andreas Brandl; Gil Goncalves; Christoph Berchtold; Markus W Büchler; Arianeb Mehrabi Journal: Surg Endosc Date: 2022-03-04 Impact factor: 3.453