| Literature DB >> 31190050 |
Maura Manion1, Dimana Dimitrova2, Luxin Pei1, Juan Gea-Banacloche3, Adrian Zelazny4, Andrea Lisco1, Christa Zerbe1, Alexandra F Freeman1, Steven M Holland1, Christopher G Kanakry2, Jennifer A Kanakry2, Irini Sereti1.
Abstract
Patients with primary immunodeficiencies undergoing allogeneic hematopoietic cell transplantation (HCT) for difficult-to-control infections can experience immune reconstitution inflammatory syndrome (IRIS) following engraftment. In 3 patients with post-HCT IRIS related to mycobacterial infection, in vitro data demonstrate the emergence of pathogen-specific immune responses and a concomitant rise in plasma inflammatory markers. Published by Oxford University Press for the Infectious Diseases Society of America 2019.Entities:
Keywords: zzm321990 Mycobacterium aviumzzm321990 ; bone marrow transplantation; immune reconstitution; primary immunodeficiency
Year: 2020 PMID: 31190050 PMCID: PMC7319264 DOI: 10.1093/cid/ciz507
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079