Literature DB >> 31189719

Twists and turns to translating 4-1BB cancer immunotherapy.

Miguel F Sanmamed1,2,3,4, Iñaki Etxeberría1, Itziar Otano1, Ignacio Melero5,2,3,4.   

Abstract

Previous shortcomings of CD137-targeted immunotherapy may be overcome by engineered bispecific agents (Claus et al, this issue).
Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Year:  2019        PMID： 31189719     DOI： 10.1126/scitranslmed.aax4738

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  17 in total

Review 1.  Signal pathways of melanoma and targeted therapy.

Authors:  Weinan Guo; Huina Wang; Chunying Li
Journal:  Signal Transduct Target Ther       Date:  2021-12-20

Review 2.  Charting roadmaps towards novel and safe synergistic immunotherapy combinations.

Authors:  Miguel F Sanmamed; Pedro Berraondo; Maria E Rodriguez-Ruiz; Ignacio Melero
Journal:  Nat Cancer       Date:  2022-06-28

Review 3.  Exploring the Mechanisms Underlying the Cardiotoxic Effects of Immune Checkpoint Inhibitor Therapies.

Authors:  Daniel Ronen; Aseel Bsoul; Michal Lotem; Suzan Abedat; Merav Yarkoni; Offer Amir; Rabea Asleh
Journal:  Vaccines (Basel)       Date:  2022-03-31

4.  Epstein-Barr virus-induced ectopic CD137 expression helps nasopharyngeal carcinoma to escape immune surveillance and enables targeting by chimeric antigen receptors.

Authors:  Mukul Prasad; Sashigala Ponnalagu; Qun Zeng; Khang Luu; Si Min Lang; Hiu Yi Wong; Man Si Cheng; Meihui Wu; Karthik Mallilankaraman; Radoslaw Mikolaj Sobota; Yan Ting Lim; Loo Chien Wang; Chuan Keng Goh; Kai Xun Joshua Tay; Kwok Seng Loh; Cheng-I Wang; Wen-Hsien Lee; Boon Cher Goh; Chwee Ming Lim; Herbert Schwarz
Journal:  Cancer Immunol Immunother       Date:  2022-03-17       Impact factor: 6.630

5.  Intratumoral Activation of 41BB Costimulatory Signals Enhances CD8 T Cell Expansion and Modulates Tumor-Infiltrating Myeloid Cells.

Authors:  Patrick Innamarato; Sarah Asby; Jennifer Morse; Amy Mackay; MacLean Hall; Scott Kidd; Luz Nagle; Amod A Sarnaik; Shari Pilon-Thomas
Journal:  J Immunol       Date:  2020-10-05       Impact factor: 5.422

Review 6.  Immunotherapies targeting stimulatory pathways and beyond.

Authors:  Julian A Marin-Acevedo; ErinMarie O Kimbrough; Rami Manochakian; Yujie Zhao; Yanyan Lou
Journal:  J Hematol Oncol       Date:  2021-05-12       Impact factor: 17.388

7.  Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer.

Authors:  Marta Trüb; Franziska Uhlenbrock; Christina Claus; Petra Herzig; Martin Thelen; Vaios Karanikas; Marina Bacac; Maria Amann; Rosemarie Albrecht; Claudia Ferrara-Koller; Daniela Thommen; Sacha Rothschield; Spasenija Savic Prince; Kirsten D Mertz; Gieri Cathomas; Robert Rosenberg; Viola Heinzelmann-Schwarz; Mark Wiese; Didier Lardinois; Pablo Umana; Christian Klein; Heinz Laubli; Abhishek S Kashyap; Alfred Zippelius
Journal:  J Immunother Cancer       Date:  2020-07       Impact factor: 13.751

8.  Dichotomous impact of affinity on the function of T cell engaging bispecific antibodies.

Authors:  Mathilde Poussin; Arlene Sereno; Xiufeng Wu; Flora Huang; Jason Manro; Shanshan Cao; Carmine Carpenito; Andrew Glasebrook; Daniel J Powell; Stephen Demarest
Journal:  J Immunother Cancer       Date:  2021-07       Impact factor: 13.751

Review 9.  Holding our breath: the promise of tissue-resident memory T cells in lung cancer.

Authors:  Claire Marceaux; Clare E Weeden; Claire L Gordon; Marie-Liesse Asselin-Labat
Journal:  Transl Lung Cancer Res       Date:  2021-06

10.  Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.

Authors:  Iñaki Etxeberria; Elixabet Bolaños; Alvaro Teijeira; Saray Garasa; Alba Yanguas; Arantza Azpilikueta; William M Kavanaugh; Olga Vasiljeva; Marcia Belvin; Bruce Howng; Bryan Irving; Kimberly Tipton; James West; Li Mei; Alan J Korman; Emanuela Sega; Irene Olivera; Assunta Cirella; Maria C Ochoa; Maria E Rodriguez; Ana Melero; Miguel F Sanmamed; John J Engelhardt; Ignacio Melero
Journal:  Proc Natl Acad Sci U S A       Date:  2021-06-29       Impact factor: 11.205
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