Literature DB >> 31184357

Development of a novel ionic liquid-curcumin complex to enhance its solubility, stability, and activity.

Md Raihan Chowdhury1, Rahman Md Moshikur, Rie Wakabayashi, Yoshiro Tahara, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto.   

Abstract

We report a one-step emulsification and rapid freeze-drying process to develop a curcumin-ionic liquid (CCM-IL) complex that could be readily dispersed in water with a significantly enhanced solubility of ∼8 mg mL-1 and half-life (t1/2) of ∼260 min compared with free CCM (solubility ∼30 nM and t1/2 ∼ 20 min). This process using an IL consisting of a long chain carbon backbone as a surfactant, may provide an alternative way of enhancing the solubility of poorly water-soluble drugs.

Entities:  

Year:  2019        PMID： 31184357     DOI： 10.1039/c9cc02812a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Ionic Liquid-In-Oil Microemulsions Prepared with Biocompatible Choline Carboxylic Acids for Improving the Transdermal Delivery of a Sparingly Soluble Drug.

Authors:  Md Rafiqul Islam; Md Raihan Chowdhury; Rie Wakabayashi; Noriho Kamiya; Muhammad Moniruzzaman; Masahiro Goto
Journal:  Pharmaceutics       Date:  2020-04-24       Impact factor: 6.321

Review 2.  Application of Ionic Liquids for Chemical Demulsification: A Review.

Authors:  Nahid Hassanshahi; Guangji Hu; Jianbing Li
Journal:  Molecules       Date:  2020-10-23       Impact factor: 4.411

Review 3.  Recent Advances in Ionic Liquids in Biomedicine.

Authors:  Alexander M Curreri; Samir Mitragotri; Eden E L Tanner
Journal:  Adv Sci (Weinh)       Date:  2021-07-10       Impact factor: 16.806

4.  Effective Oxidation-Responsive Polyester Nanocarriers for Anti-Inflammatory Drug Delivery.

Authors:  Pan He; Bingtong Tang; Yusheng Li; Yu Zhang; Xinming Liu; Xin Guo; Dong Wang; Peng She; Chunsheng Xiao
Journal:  Int J Nanomedicine       Date:  2021-07-27
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.