| Literature DB >> 31182810 |
Guoqiang Li1, Jiyang Zhou1, Haiyan Jia1, Zhongxia Gao1, Min Fan1, Yanjun Luo1, Panting Zhao1, Shulin Xue1,2, Na Li1, Yang Yuan1, Shengwei Ma1, Zhongxin Kong1, Li Jia1, Xia An1,3, Ge Jiang1, Wenxing Liu1, Wenjin Cao1, Rongrong Zhang1, Jicai Fan1, Xiaowu Xu1, Yanfang Liu1, Qianqian Kong1, Shouhang Zheng1,4, Yao Wang1, Bin Qin1, Shouyang Cao1, Yunxiao Ding1, Jinxing Shi1, Haisheng Yan1, Xin Wang1, Congfu Ran1, Zhengqiang Ma5.
Abstract
Head or ear blight, mainly caused by Fusarium species, can devastate almost all staple cereal crops (particularly wheat), resulting in great economic loss and imposing health threats on both human beings and livestock1-3. However, achievement in breeding for highly resistant cultivars is still not satisfactory. Here, we isolated the major-effect wheat quantitative trait locus, Qfhs.njau-3B, which confers head blight resistance, and showed that it is the same as the previously designated Fhb1. Fhb1 results from a rare deletion involving the 3' exon of the histidine-rich calcium-binding-protein gene on chromosome 3BS. Both wheat and Arabidopsis transformed with the Fhb1 sequence showed enhanced resistance to Fusarium graminearum spread. The translation products of this gene's homologs among plants are well conserved and might be essential for plant growth and development. Fhb1 could be useful not only for curbing Fusarium head blight in grain crops but also for improving other plants vulnerable to Fusarium species.Entities:
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Year: 2019 PMID： 31182810 DOI： 10.1038/s41588-019-0426-7
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330