Literature DB >> 31182345

Type IV Pili as a Therapeutic Target.

Guillaume Duménil1.   

Abstract

In the age of antibiotic resistance, strategies targeting virulence traits of bacteria are the focus of intense study. Two such studies came out independently a week apart showing that bacterial type IV pili are a promising therapeutic target.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Keywords:  antibiotic resistance; antivirulence; meningitis; sepsis; type IV pili

Mesh:

Substances:

Year:  2019        PMID: 31182345     DOI: 10.1016/j.tim.2019.05.005

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  3 in total

1.  Characterization of Pseudomonas aeruginosa Bacteriophage L5 Which Requires Type IV Pili for Infection.

Authors:  Lan Yang; Tingting Zhang; Linlin Li; Chao Zheng; Demeng Tan; Nannan Wu; Mingyang Wang; Tongyu Zhu
Journal:  Front Microbiol       Date:  2022-07-01       Impact factor: 6.064

2.  Treatment of Wound Infections in a Mouse Model Using Zn2+-Releasing Phage Bound to Gold Nanorods.

Authors:  Huan Peng; Daniele Rossetto; Sheref S Mansy; Maria C Jordan; Kenneth P Roos; Irene A Chen
Journal:  ACS Nano       Date:  2022-03-03       Impact factor: 15.881

Review 3.  Structure and function of minor pilins of type IV pili.

Authors:  Theis Jacobsen; Benjamin Bardiaux; Olivera Francetic; Nadia Izadi-Pruneyre; Michael Nilges
Journal:  Med Microbiol Immunol       Date:  2019-11-29       Impact factor: 3.402

  3 in total

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