| Literature DB >> 311821 |
M Popescu, J Löhler, F Lehmann-Grube.
Abstract
The infectivity of blood and lymphoid organs of mice persistently infected with lymphocytic choriomeningitis virus was found to be predominantly associated with lymphocytes and both T and B cells were infectious. A hypothesis is presented in which it is assumed that lymphocytes in carrier mice are infected via their LCM virus-specific antigen receptors, thereby leading to their antigen-triggered clonal expansion followed by infection and functional inactivation.Entities:
Mesh:
Year: 1979 PMID: 311821 DOI: 10.1099/0022-1317-42-3-481
Source DB: PubMed Journal: J Gen Virol ISSN: 0022-1317 Impact factor: 3.891