Literature DB >> 31181944

Chronic dissecting aneurysm of ascending aorta with a large intramural thrombus and isolated aortic defects.

Silvia Iannaccone Farkašová, Dorota Sopková, Marián Švajdler, Daniel Farkaš, Lucia Mistríková, Roman Mezencev.   

Abstract

We present macroscopic and microscopic findings in a case of chronic dissecting aneurysm of ascending aorta and aortic arch associated with isolated tears of aortic wall without its rupture in a 71-year-old female presenting with minimal clinical symptomatology. Aneurysmal dilation of the aorta was caused not only by the bridging of the vascular wall based on the presence of an organizing intramural thrombus in the false lumen between the separated layers, but also by a wide flat defect in the aortic intima and media with the preservation of the aortic wall integrity due to fibrotical alteration of tunica adventicia. Histologic examination of the thoracic aorta detected cystic medial degeneration with mild atherosclerosis.

Entities:  

Keywords:  aortic dissection; aortic intramural thrombus; dissecting aortic aneurysm; medial degeneration; mucoid extracellular matrix accumulation

Mesh:

Year:  2019        PMID: 31181944

Source DB:  PubMed          Journal:  Cesk Patol        ISSN: 1210-7875


  1 in total

1.  ALDH2 knockout protects against aortic dissection.

Authors:  Chentao Luo; Bing Zhou; Yong Cui; Zhifang Liu; Shuwei Wang
Journal:  BMC Cardiovasc Disord       Date:  2022-10-13       Impact factor: 2.174

  1 in total

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