Literature DB >> 31181923

Guitarrins A-E and Aluminumguitarrin A: 5-Azaindoles from the Northwestern Pacific Marine Sponge Guitarra fimbriata.

Alla G Guzii1, Tatyana N Makarieva1, Vladimir A Denisenko1, Andrey V Gerasimenko2, Anatoly A Udovenko2, Roman S Popov1, Pavel S Dmitrenok1, Vasily A Golotin1, Sergey N Fedorov1, Boris B Grebnev1, Valentin A Stonik1.   

Abstract

Guitarrins A-E (1-5), the first natural 5-azaindoles, and aluminumguitarrin A (1a), the first aluminum-containing compound from marine invertebrates, were isolated from the sponge Guitarra fimbriata. The structures of these compounds were established using detailed analysis of 1D and 2D NMR data, mass spectra, and X-ray analysis of 1 and 1a. Compound 3 was proved to be a natural inhibitor of alkaline phosphatase.

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Year:  2019        PMID: 31181923     DOI: 10.1021/acs.jnatprod.9b00334

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  4 in total

1.  New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein.

Authors:  Sergey A Dyshlovoy; Larisa K Shubina; Tatyana N Makarieva; Jessica Hauschild; Nadja Strewinsky; Alla G Guzii; Alexander S Menshov; Roman S Popov; Boris B Grebnev; Tobias Busenbender; Su Jung Oh-Hohenhorst; Tobias Maurer; Derya Tilki; Markus Graefen; Carsten Bokemeyer; Valentin A Stonik; Gunhild von Amsberg
Journal:  Sci Rep       Date:  2022-08-09       Impact factor: 4.996

2.  Gracilosulfates A-G, Monosulfated Polyoxygenated Steroids from the Marine Sponge Haliclona gracilis.

Authors:  Larisa K Shubina; Tatyana N Makarieva; Vladimir A Denisenko; Roman S Popov; Sergey A Dyshlovoy; Boris B Grebnev; Pavel S Dmitrenok; Gunhild von Amsberg; Valentin A Stonik
Journal:  Mar Drugs       Date:  2020-08-30       Impact factor: 5.118

Review 3.  Marine Indole Alkaloids-Isolation, Structure and Bioactivities.

Authors:  Yong Hu; Siling Chen; Fang Yang; Shuai Dong
Journal:  Mar Drugs       Date:  2021-11-24       Impact factor: 5.118

Review 4.  Marine-Derived Indole Alkaloids and Their Biological and Pharmacological Activities.

Authors:  Joko Tri Wibowo; Peni Ahmadi; Siti Irma Rahmawati; Asep Bayu; Masteria Yunovilsa Putra; Anake Kijjoa
Journal:  Mar Drugs       Date:  2021-12-21       Impact factor: 5.118

  4 in total

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