Literature DB >> 31181420

The functional organisation of the hippocampus along its long axis is gradual and predicts recollection.

Izabela Przeździk1, Myrthe Faber2, Guillén Fernández3, Christian F Beckmann4, Koen V Haak5.   

Abstract

Understanding the functional organisation of the hippocampus is crucial for understanding its role in cognition and disorders in which it is implicated. Different views have been proposed of how function is distributed along its long axis: one view suggests segregation, whereas the alternative view postulates a more gradual organisation. Here, we applied a novel 'connectopic mapping' data-analysis approach to the resting-state fMRI data of participants of the Human Connectome Project, and demonstrate that the functional organisation of the hippocampal longitudinal axis is gradual rather than segregated into parcels. In addition, we show that inter-individual variations in this gradual organisation predict variations in recollection memory better than a characterisation based on functional parcellation. These results present an important step forward in understanding the functional organisation of the human hippocampus and have important implications for translating between rodent and human research.
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Connectivity gradient; Connectopic mapping; Hippocampus; Longitudinal axis; Recollection

Mesh:

Year:  2019        PMID: 31181420     DOI: 10.1016/j.cortex.2019.04.015

Source DB:  PubMed          Journal:  Cortex        ISSN: 0010-9452            Impact factor:   4.027


  20 in total

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Journal:  Commun Biol       Date:  2020-03-05

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Review 3.  Parsing the Network Mechanisms of Electroconvulsive Therapy.

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Review 4.  Cortico-Limbic Interactions Mediate Adaptive and Maladaptive Responses Relevant to Psychopathology.

Authors:  Rothem Kovner; Jonathan A Oler; Ned H Kalin
Journal:  Am J Psychiatry       Date:  2019-12-01       Impact factor: 18.112

5.  A Structure-Function Substrate of Memory for Spatial Configurations in Medial and Lateral Temporal Cortices.

Authors:  Shahin Tavakol; Qiongling Li; Jessica Royer; Reinder Vos de Wael; Sara Larivière; Alex Lowe; Casey Paquola; Elizabeth Jefferies; Tom Hartley; Andrea Bernasconi; Neda Bernasconi; Jonathan Smallwood; Veronique Bohbot; Lorenzo Caciagli; Boris Bernhardt
Journal:  Cereb Cortex       Date:  2021-06-10       Impact factor: 5.357

6.  Functional Connectivity during Encoding Predicts Individual Differences in Long-Term Memory.

Authors:  Qi Lin; Kwangsun Yoo; Xilin Shen; Todd R Constable; Marvin M Chun
Journal:  J Cogn Neurosci       Date:  2021-10-01       Impact factor: 3.225

7.  Distinct and Common Large-Scale Networks of the Hippocampal Long Axis in Older Age: Links to Episodic Memory and Dopamine D2 Receptor Availability.

Authors:  Kristin Nordin; Lars Nyberg; Micael Andersson; Nina Karalija; Katrine Riklund; Lars Bäckman; Alireza Salami
Journal:  Cereb Cortex       Date:  2021-06-10       Impact factor: 5.357

8.  Intrinsic connectivity reveals functionally distinct cortico-hippocampal networks in the human brain.

Authors:  Alexander J Barnett; Walter Reilly; Halle R Dimsdale-Zucker; Eda Mizrak; Zachariah Reagh; Charan Ranganath
Journal:  PLoS Biol       Date:  2021-06-02       Impact factor: 8.029

Review 9.  Functional differentiation in the transverse plane of the hippocampus: An update on activity segregation within the DG and CA3 subfields.

Authors:  Mariah A A Meyer; Jelena Radulovic
Journal:  Brain Res Bull       Date:  2021-03-13       Impact factor: 3.715

10.  Reward anticipation selectively boosts encoding of gist for visual objects.

Authors:  Liyana T Swirsky; Ryan M Marinacci; Julia Spaniol
Journal:  Sci Rep       Date:  2020-11-19       Impact factor: 4.379

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