Literature DB >> 31179746

Reconstruction of Nasal Defects With Dermal Skin Substitutes-A Retrospective Study of 36 Defects.

Katharina Moratin1, Philipp-Sebastian Koch1,2, Johannes Benecke1, Azadeh Orouji1, Corinne Bauer1,3,4, Jörg Faulhaber5, Wolfgang Koenen6, Moritz Felcht1,4.   

Abstract

OBJECTIVES: It is uncertain whether dermal regeneration templates (DRTs) are helpful to reconstruct nasal defects. The aim of this study was to assess whether the aesthetic subunits determine the outcome.
METHODS: In this unicentric, retrospective study, the surgical procedures and outcomes of patients who received DRTs to reconstruct nasal defects were assessed and compared with the involved aesthetic subunits.
RESULTS: DRTs were used for reconstruction of 36 nasal defects in 35 patients with involvement of 76 aesthetic subunits: nasal sidewall (n = 21), nasal ala (n = 13), nasal tip/columella (n = 12, n = 1, respectively), nasal dorsum (n = 12), and extranasal aesthetic areas (n = 17). Fifty-eight nasal and 8 extranasal aesthetic subunits were reconstructed with DRTs, 10 subunits with a flap. Twenty-nine of 36 defects healed without any complications (80.5%). All reconstructed nasal tips/columella and the nasal dorsa healed without any complications. Region-specific complications were retraction of the ala rim (4/12; 33.3% of the patients with involvement of the nasal ala) and the formation of a fistula in the nasal sidewall (1/21; 4.8%). Region-specific complications of extranasal subunits were the development of an ectropium (2/3; 66.7% of the patients with involvement of the lower lid).
CONCLUSIONS: DRTs can be helpful to reconstruct nasal defects. However, if the defect involves the aesthetic subunits nasal ala or the infraorbital region, different techniques should be preferred.

Entities:  

Keywords:  Integra; Matriderm; artificial skin; nasal defect; skin substitute

Mesh:

Substances:

Year:  2019        PMID: 31179746     DOI: 10.1177/1203475419852060

Source DB:  PubMed          Journal:  J Cutan Med Surg        ISSN: 1203-4754            Impact factor:   2.092


  2 in total

Review 1.  Technical Refinements with the Use of Biologic Healing Agents.

Authors:  Rami P Dibbs; Monal Depani; James F Thornton
Journal:  Semin Plast Surg       Date:  2022-02-25       Impact factor: 2.195

2.  Complete division of the pedicle of the forehead flap is possible after 1 week of engraftment in selected patients.

Authors:  Moritz Felcht; Tino Wetzig
Journal:  JAAD Int       Date:  2020-11-30
  2 in total

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