Literature DB >> 31178058

PHASER: A platform for clinical translation of FLASH cancer radiotherapy.

Peter G Maxim1, Sami G Tantawi2, Billy W Loo3.   

Abstract

Pluridirectional high-energy agile scanning electronic radiotherapy (PHASER) is next-generation medical linac technology for ultra-rapid highly conformal image-guided radiation, fast enough to "freeze" physiological motion, affording improved accuracy, precision, and potentially superior FLASH radiobiological therapeutic index. Designed for compactness, economy, and clinical efficiency, it is also intended to address barriers to global access to curative radiotherapy.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  FLASH; PHASER; Ultra-rapid radiation therapy; Very high-energy electron radiotherapy

Mesh：

Year:  2019        PMID： 31178058     DOI： 10.1016/j.radonc.2019.05.005

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN： 0167-8140            Impact factor:   6.280


  22 in total

1.  A conceptual study on real-time adaptive radiation therapy optimization through ultra-fast beamlet control.

Authors:  Rodney D Wiersma; Xinmin Liu
Journal:  Biomed Phys Eng Express       Date:  2019-08-30

2.  Development of Ultra-High Dose-Rate (FLASH) Particle Therapy.

Authors:  Michele M Kim; Arash Darafsheh; Jan Schuemann; Ivana Dokic; Olle Lundh; Tianyu Zhao; José Ramos-Méndez; Lei Dong; Kristoffer Petersson
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2021-06-22

Review 3.  Optimizing Radiation Therapy to Boost Systemic Immune Responses in Breast Cancer: A Critical Review for Breast Radiation Oncologists.

Authors:  Alice Y Ho; Jean L Wright; Rachel C Blitzblau; Robert W Mutter; Dan G Duda; Larry Norton; Aditya Bardia; Laura Spring; Steven J Isakoff; Jonathan H Chen; Clemens Grassberger; Jennifer R Bellon; Sushil Beriwal; Atif J Khan; Corey Speers; Samantha A Dunn; Alastair Thompson; Cesar A Santa-Maria; Ian E Krop; Elizabeth Mittendorf; Tari A King; Gaorav P Gupta
Journal:  Int J Radiat Oncol Biol Phys       Date:  2020-05-14       Impact factor: 7.038

4.  The Importance and Clinical Implications of FLASH Ultra-High Dose-Rate Studies for Proton and Heavy Ion Radiotherapy.

Authors:  Nicholas W Colangelo; Edouard I Azzam
Journal:  Radiat Res       Date:  2019-10-28       Impact factor: 2.841

5.  Initial Steps Towards a Clinical FLASH Radiotherapy System: Pediatric Whole Brain Irradiation with 40 MeV Electrons at FLASH Dose Rates.

Authors:  Dylan Yamabe Breitkreutz; Muhammad Shumail; Karl K Bush; Sami G Tantawi; Peter G Maxime; Billy W Loo
Journal:  Radiat Res       Date:  2020-12-01       Impact factor: 2.841

Review 6.  Stereotactic radiotherapy for early stage non-small cell lung cancer: current standards and ongoing research.

Authors:  Eugenia Vlaskou Badra; Michael Baumgartl; Silvia Fabiano; Aurélien Jongen; Matthias Guckenberger
Journal:  Transl Lung Cancer Res       Date:  2021-04

7.  FLASH Irradiation Results in Reduced Severe Skin Toxicity Compared to Conventional-Dose-Rate Irradiation.

Authors:  Luis A Soto; Kerriann M Casey; Jinghui Wang; Alexandra Blaney; Rakesh Manjappa; Dylan Breitkreutz; Lawrie Skinner; Suparna Dutt; Ryan B Ko; Karl Bush; Amy S Yu; Stavros Melemenidis; Samuel Strober; Edgar Englemann; Peter G Maxim; Edward E Graves; Billy W Loo
Journal:  Radiat Res       Date:  2020-12-01       Impact factor: 2.841

8.  Evaluating the Reproducibility of Mouse Anatomy under Rotation in a Custom Immobilization Device for Conformal FLASH Radiotherapy.

Authors:  Ryan B Ko; Luis A Soto; Rie von Eyben; Stavros Melemenidis; Erinn B Rankin; Peter G Maxim; Edward E Graves; Billy W Loo
Journal:  Radiat Res       Date:  2020-12-01       Impact factor: 2.841

9.  ROAD: ROtational direct Aperture optimization with a Decoupled ring-collimator for FLASH radiotherapy.

Authors:  Qihui Lyu; Ryan Neph; Daniel O'Connor; Dan Ruan; Salime Boucher; Ke Sheng
Journal:  Phys Med Biol       Date:  2021-01-29       Impact factor: 3.609

10.  Focused VHEE (very high energy electron) beams and dose delivery for radiotherapy applications.

Authors:  L Whitmore; R I Mackay; M van Herk; J K Jones; R M Jones
Journal:  Sci Rep       Date:  2021-07-07       Impact factor: 4.379
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