Literature DB >> 311775

Antithyroglobulin (ATG) production by peripheral blood leukocytes in vitro.

G N Beall, S R Kruger.   

Abstract

Antithyroglobulin is produced in vitro by pokeweed mitogen stimulation of peripheral blood lymphocytes from patients whose serum contains the autoantibody. Antithyroglobulin synthesis requires T lymphocyte help but is suppressed by larger numbers of T lymphocytes. T cells from both patients and normals perform both of these functions.

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Year:  1979        PMID: 311775     DOI: 10.1210/jcem-48-4-712

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


  7 in total

1.  Spontaneous secretion of thyroid autoantibodies by cultured peripheral blood lymphocytes from patients with Hashimoto's thyroiditis detected by micro-ELISA techniques.

Authors:  P Benveniste; B E Wenzel; A Khalil; V V Row; R Volpé
Journal:  Clin Exp Immunol       Date:  1984-11       Impact factor: 4.330

2.  Severe combined immunodeficient (SCID) mice: a model for investigating human thyroid autoantibody synthesis.

Authors:  L Macht; N Fukuma; K Leader; D Sarsero; C A Pegg; D I Phillips; P Yates; S M McLachlan; C Elson; B Rees Smith
Journal:  Clin Exp Immunol       Date:  1991-04       Impact factor: 4.330

3.  Self-reactive CD4+ T cells and B cells in the blood in health and autoimmune disease: increased frequency of thyroglobulin-reactive cells in Graves' disease.

Authors:  Claus H Nielsen; Ane Christine Moeller; Laszlo Hegedüs; Klaus Bendtzen; R Graham Q Leslie
Journal:  J Clin Immunol       Date:  2006-04-07       Impact factor: 8.317

4.  Production of human anti-thyroglobulin in vitro. III. The role of immunoglobulin-bearing cells.

Authors:  G N Beall; S R Kruger
Journal:  Clin Exp Immunol       Date:  1981-07       Impact factor: 4.330

5.  10 years experience with consecutive measurement of thyrotropin binding inhibiting antibodies (TBIAb).

Authors:  J Hensen; P Kotulla; R Finke; K Badenhoop; K Koppenhagen; H Meinhold; H Schleusener
Journal:  J Endocrinol Invest       Date:  1984-06       Impact factor: 4.256

6.  A new solid-phase immunoradiometric assay for anti-thyroglobulin autoantibody.

Authors:  S Mariotti; S Pisani; A Russova; A Pinchera
Journal:  J Endocrinol Invest       Date:  1982 Jul-Aug       Impact factor: 4.256

7.  In vitro detection of anti-thyroglobulin antibody forming cells from the lymphocytes of chronic thyroiditis patients and analysis of their regulation.

Authors:  T Noma; J Yata; Y Shishiba; B Inatsuki
Journal:  Clin Exp Immunol       Date:  1982-09       Impact factor: 4.330

  7 in total

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