Literature DB >> 31177291

Correlation between hip osteoarthritis and proximal femoral fracture site: could it be protective for intracapsular neck fractures? A retrospective study on 320 cases.

Tommaso Maluta1, Giovanna Toso2, Stefano Negri2, Elena Manuela Samaila2, Bruno Magnan2.   

Abstract

Proximal femoral fractures affect elderly people, showing high morbidity and mortality incidence resulting in a major economic burden on national healthcare systems. Understanding the causes of these injuries is of paramount importance to prevent the serious consequences of these fractures.
INTRODUCTION: Hip osteoarthritis and proximal femoral fractures mainly affect elderly patients. Several authors, in their studies, tried to document a correlation between these conditions, but the results are conflicting. The aim of this study was to evaluate the relationship between hip osteoarthritis and the fracture site. Secondly, to evaluate if the grade of osteoarthritis could influence the fracture pattern.
METHODS: A retrospective study on 320 patients admitted for hip fracture between June 2015 and December 2016 was carried on. Radiographic images were evaluated, assessing the type of fracture, presence and grade of osteoarthritis according to Kellgren-Lawrence and Tönnis classifications, and their correlations.
RESULTS: Osteoarthritis was found to affect the fracture site showing a higher prevalence among subjects with extracapsular than those with intracapsular fractures (p < 0.00001). Patients with radiographic signs of arthritis had mainly trochanteric fracture. Conversely, patients without arthritis more frequently presented a femoral neck fracture. This correlation was even more significant as the severity of the OA increased.
CONCLUSIONS: Results support the hypothesis that hip osteoarthritis could represent a protective factor for intracapsular fractures and a risk factor for trochanteric ones. The severity of arthritis is also associated with the fracture pattern.

Entities:  

Keywords:  Extracapsular fractures; Hip osteoarthritis; Intracapsular fractures; Proximal femur fractures

Mesh:

Year:  2019        PMID: 31177291     DOI: 10.1007/s00198-019-05015-5

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  5 in total

Review 1.  Prevalence and treatment rate of osteoporosis in patients undergoing total knee and hip arthroplasty: a systematic review and meta-analysis.

Authors:  Pei-Lun Xiao; Chi-Jen Hsu; Yong-Guang Ma; Ding Liu; Rong Peng; Xiang-He Xu; Hua-Ding Lu
Journal:  Arch Osteoporos       Date:  2022-01-14       Impact factor: 2.617

2.  Hip structure analysis and femoral osteodensitometry in aged postmenopausal women with hip osteoarthritis and femoral neck fracture.

Authors:  Jelena Jadzic; Slavisa Zagorac; Marija Djuric; Danijela Djonic
Journal:  Int Orthop       Date:  2022-10-12       Impact factor: 3.479

3.  MicroRNA-197-3p Inhibits the Osteogenic Differentiation in Osteoporosis by Down-Regulating KLF 10.

Authors:  Murong You; Liang Zhang; Xiaoxiang Zhang; Yang Fu; Xieping Dong
Journal:  Clin Interv Aging       Date:  2021-01-11       Impact factor: 4.458

4.  Long non-coding RNA XIST promotes osteoporosis by inhibiting the differentiation of bone marrow mesenchymal stem cell by sponging miR-29b-3p that suppresses nicotinamide N-methyltransferase.

Authors:  Jiang Yu; Min Xiao; Guohai Ren
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

5.  Knockdown of long non-coding RNA HOTAIR promotes bone marrow mesenchymal stem cell differentiation by sponging microRNA miR-378g that inhibits nicotinamide N-methyltransferase.

Authors:  Wei Wang; Tao Li; Shibo Feng
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

  5 in total

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