Literature DB >> 31177236

An exploratory investigation of the effect of naturalistic light on depression, anxiety, and cognitive outcomes in stroke patients during admission for rehabilitation: A randomized controlled trial.

Anders West1,2, Sofie Amalie Simonsen1, Alexander Zielinski1, Niklas Cyril1, Marie Schønsted1, Poul Jennum2,3, Birgit Sander2,4, Helle K Iversen1,2.   

Abstract

BACKGROUND: Patients admitted for rehabilitation often lack sufficient natural light to entrain their circadian rhythm.
OBJECTIVE: Installed diurnal naturalistic light may positively influence the outcome of depressive mood, anxiety, and cognition in such patients.
METHODS: A quasi-randomized controlled trial. Ninety stroke patients in need of rehabilitation were randomized between May 1, 2014, and June 1, 2015 to either a rehabilitation unit equipped entirely with always on naturalistic lighting (IU), or to a rehabilitation unit with standard indoor lighting (CU).Examinations were performed at inclusion and discharge. The following changes were investigated: depressive mood based on the Hamilton Depression scale (HAM-D6) and Major Depression Inventory scale (MDI), anxiety based on the Hospital Anxiety and Depression Scale (HADS), cognition based on the Montreal Cognitive Assessment (MoCA) and well-being based on the Well-being Index (WHO-5).
RESULTS: Depressive mood (MDI p = 0.0005, HAM-D6 p = 0.011) and anxiety (HADS anxiety p = 0.045) was reduced, and well-being (WHO-5 p = 0.046) was increased, in the IU at discharge compared to the CU. No difference was found in cognition (MoCA p = 0.969).
CONCLUSIONS: This study is the first to demonstrate that exposure to naturalistic light during admission may significantly improve mental health in rehabilitation patients. Further studies are needed to confirm these findings.

Entities:  

Keywords:  Circadian rhythm; anxiety; clinical trial; cognitive; depression; light; stroke

Mesh:

Year:  2019        PMID: 31177236     DOI: 10.3233/NRE-182565

Source DB:  PubMed          Journal:  NeuroRehabilitation        ISSN: 1053-8135            Impact factor:   2.138


  4 in total

Review 1.  Developments in treating the nonmotor symptoms of stroke.

Authors:  Argye E Hillis
Journal:  Expert Rev Neurother       Date:  2020-05-12       Impact factor: 4.618

2.  Dynamic LED-light versus static LED-light for depressed inpatients: study protocol for a randomised clinical study.

Authors:  Carlo Volf; Anne Sofie Aggestrup; Paul Michael Petersen; Carsten Dam-Hansen; Ulla Knorr; Ema Erkocevic Petersen; Janus Engstrøm; Janus C Jakobsen; Torben Skov Hansen; Helle Østergaard Madsen; Ida Hageman; Klaus Martiny
Journal:  BMJ Open       Date:  2020-01-26       Impact factor: 2.692

Review 3.  Disruptions of Circadian Rhythms and Thrombolytic Therapy During Ischemic Stroke Intervention.

Authors:  Jennifer A Liu; James C Walton; A Courtney DeVries; Randy J Nelson
Journal:  Front Neurosci       Date:  2021-06-10       Impact factor: 4.677

4.  Dynamic LED light versus static LED light for depressed inpatients: results from a randomized feasibility trial.

Authors:  Carlo Volf; Anne Sofie Aggestrup; Signe Dunker Svendsen; Torben Skov Hansen; Paul Michael Petersen; Carsten Dam-Hansen; Ulla Knorr; Ema Erkocevic Petersen; Janus Engstrøm; Ida Hageman; Janus Christian Jakobsen; Klaus Martiny
Journal:  Pilot Feasibility Stud       Date:  2020-01-15
  4 in total

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