| Literature DB >> 3117583 |
J D Milner1, D K Reinstein, R J Wurtman.
Abstract
Unilateral nigrostriatal lesions in rats that almost totally depleted striatal dopamine had no effect on striatal levels of dopamine's precursor, tyrosine, nor on those of leucine. Since prolonged electrical stimulation of the slices markedly depletes them of tyrosine (1,2) we conclude that tyrosine can be mobilized from non-dopaminergic striatal cells to augment dopamine release.Entities:
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Year: 1987 PMID： 3117583 DOI： 10.1007/bf01956051
Source DB: PubMed Journal: Experientia ISSN： 0014-4754