Literature DB >> 31175507

Pyrene Based Fluorescent Turn-on Chemosensor for Sequential Detection of Fe3+ and Fe2+ Ions and its Application in Live Cell Imaging.

Rajasekaran Dhivya1, Asaithambi Gomathi1, Periasamy Viswanathamurthi2.   

Abstract

A simple pyrene-based "turn-on" chemosensor bearing isonizide namely 3-(pyren-1-yl methylene) pentane-2,4-diyldene di(isonicotinohydrazide) (PMPD) was designed and synthesized for detecting Fe3+and Fe2+ ions in HEPES buffer solution at pH 7.4 (DMSO: H2O (1:9 v/v)) medium. The probe shows conducive selectivity for Fe2+ and Fe3+ ions over the other competitive metal cations. The detection limit was found to be 1.67 μM for Fe3+ and 2.02 μM for Fe2+. The recognition mechanism of PMPD towards Fe3+ and Fe2+ has been examined in detail by absorption, emission, and ESI-MS studies. Moreover, "turn-on" fluorescence behavior of the probe was used to track iron ions in living cells.

Entities:  

Keywords:  Cell imaging; Fluorescence probe; Iron ions; Schiff base

Mesh：

Substances：

Year:  2019        PMID： 31175507     DOI： 10.1007/s10895-019-02392-2

Source DB:  PubMed          Journal:  J Fluoresc        ISSN： 1053-0509            Impact factor:   2.217


  14 in total

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  1 in total

1.  Simple Fluorescence Sensing Approach for Selective Detection of Fe3+ Ions: Live-Cell Imaging and Logic Gate Functioning.

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Journal:  ACS Omega       Date:  2022-09-12
  1 in total

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