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Literature DB >> 3117537

Beta-lactamase alteration of beta-lactam inhibitory zones.

Abstract

A disk approximation test, in which the inhibitory zone of one beta-lactam antibiotic is truncated under influence of another beta-lactam (e.g. cefoxitin), was used as a screen for the presence of inducible beta-lactamase. By using beta-lactamase extracts and a specific inhibitor, it was shown that chromosomal beta-lactamase can indeed be the sole cause of truncated beta-lactam inhibitory zones.

Entities: Chemical

Mesh：

Substances：

Year: 1987 PMID： 3117537 DOI： 10.1007/bf02013113

Source DB: PubMed Journal: Eur J Clin Microbiol ISSN： 0722-2211 Impact factor: 3.267

9 in total

1. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

Review 2. Emergence of resistance during therapy with the newer beta-lactam antibiotics: role of inducible beta-lactamases and implications for the future.

Authors: C C Sanders; W E Sanders
Journal: Rev Infect Dis Date: 1983 Jul-Aug

1 in total

Review 1. Clinical importance of inducible beta-lactamases in gram-negative bacteria.

Authors: C C Sanders; W E Sanders
Journal: Eur J Clin Microbiol Date: 1987-08 Impact factor: 3.267

1 in total

Beta-lactamase alteration of beta-lactam inhibitory zones.

1. Protein measurement with the Folin phenol reagent.

Review 2. Emergence of resistance during therapy with the newer beta-lactam antibiotics: role of inducible beta-lactamases and implications for the future.

3. The role of inducible beta-lactamases in the antagonism seen with certain cephalosporin combinations.

4. Induction of beta-lactamase by various beta-lactam antibiotics in Enterobacter cloacae.

5. Double beta-lactam therapy in the immunocompromised host.

6. Pseudomonas aeruginosa beta-lactamase as a defence against azlocillin, mezlocillin and piperacillin.

7. Antagonism of carbenicillin and cefamandole by cefoxitin in treatment of experimental infections in mice.

8. Imipenem-induced resistance to antipseudomonal beta-lactams in Pseudomonas aeruginosa.

9. In vitro and in vivo antibacterial effects of combinations of beta-lactam antibiotics.

Review 1. Clinical importance of inducible beta-lactamases in gram-negative bacteria.