Fahed Darmoch1, M Chadi Alraies2, Yasser Al-Khadra3, Homam Moussa Pacha4, Mohamad Soud4, Amir Kaki5, Tanveer Rab6, Cindy L Grines7, Rodrigo Bagur8, Chun Shing Kwok9, Mamas Mamas9, Subhash Banerjee10, Wael AlJaroudi11, Duane S Pinto1. 1. Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts. 2. Wayne State University, Detroit Medical Center, Detroit, Michigan. Electronic address: alraies@hotmail.com. 3. Cleveland Clinic Foundation, Cleveland, Ohio. 4. MedStar Washington Hospital Center, Washington, District of Columbia. 5. St John Hospital and Medical Center, Detroit, Michigan. 6. Emory University, Atlanta, Georgia. 7. Zucker School of Medicine at Hofstra Northwell Health, Northshore University Hospital, Manhasset New York. 8. London Health Sciences Centre, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry Western University, London, Ontario, Canada. 9. Keele Cardiovascular Research Group, Keele University, Stoke-on-Trent, United Kingdom; Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom. 10. University of Texas Southwestern Medical Center, Dallas, Texas. 11. Division of Cardiovascular Medicine, Clemenceau Medical Center, Beirut, Lebanon.
Abstract
Peripheral vascular disease (PVD) is common in patients referred for transcatheter aortic valve implantation (TAVI). We sought to investigate the impact of PVD on patients who underwent TAVI. Using data from the National Inpatient Sample database 2011 and 2014, we identified patients who had undergone TAVI. We studied the clinical characteristics and procedural outcomes in patients with PVD who underwent TAVI compared with those patients without PVD using propensity score matching score matching. Results: A total of 42,215 patients underwent TAVI; of which 1,388 patients were matched using propensity score matched scores to 694 in each (PVD vs no PVD) patients. The population had a mean age of 81 years old and 55.8% were of female gender. African-Americans constituted 4.3%. PVD patients who underwent TAVI were found to have higher rates of vascular complications (11.8% vs 5.9 % p <0.001) compared with non-PVD patients and tended to have higher mortality (5.5% vs 3.6%, p = 0.121) and post-TAVI bleeding (13.5% vs 12% p = 0.143). In conclusion, PVD patients have higher in-hospital mortality and higher incidence of in-hospital overall complications compared with patients who have no PVD.
Peripheral vascular disease (PVD) is common in patients referred for transcatheter aortic valve implantation (TAVI). We sought to investigate the impact of PVD on patients who underwent TAVI. Using data from the National Inpatient Sample database 2011 and 2014, we identified patients who had undergone TAVI. We studied the clinical characteristics and procedural outcomes in patients with PVD who underwent TAVI compared with those patients without PVD using propensity score matching score matching. Results: A total of 42,215 patients underwent TAVI; of which 1,388 patients were matched using propensity score matched scores to 694 in each (PVD vs no PVD) patients. The population had a mean age of 81 years old and 55.8% were of female gender. African-Americans constituted 4.3%. PVD patients who underwent TAVI were found to have higher rates of vascular complications (11.8% vs 5.9 % p <0.001) compared with non-PVD patients and tended to have higher mortality (5.5% vs 3.6%, p = 0.121) and post-TAVI bleeding (13.5% vs 12% p = 0.143). In conclusion, PVD patients have higher in-hospital mortality and higher incidence of in-hospital overall complications compared with patients who have no PVD.