Size and location of tumors influencing the effect of bladder instillation therapy.

The clinical results obtained in 81 cases of bladder tumor are used as a basis for discussion of factors influencing the effect of bladder instillation therapy. The following conclusions are derived: 1) If bladder instillation therapy aims only at complete remission (CR), tumors over 1 cm in diameter should be excluded, because this is the theoretical size limit beyond which instillation therapy cannot lead to CR. 2) At least 40 ml of drugs may be needed for instillation therapy for tumors located in area B, the limited part posterior to the trigonum.