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Literature DB >> 31173711

Breakthrough Moments: Yoshiki Sasai's Discoveries in the Third Dimension.

Abstract

Yoshiki Sasai pioneered the organoid field with his idea of mimicking embryonic development in 3D. We shine a spotlight on his seminal work describing how the innate ability of embryonic stem cells to self-organize into layers and grow in a polarized fashion fosters their appropriate differentiation and response to morphogens.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2019 PMID： 31173711 PMCID： PMC7085937 DOI： 10.1016/j.stem.2019.05.007

Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633

10 in total

1. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex.

Authors: Taisuke Kadoshima; Hideya Sakaguchi; Tokushige Nakano; Mika Soen; Satoshi Ando; Mototsugu Eiraku; Yoshiki Sasai
Journal: Proc Natl Acad Sci U S A Date: 2013-11-25 Impact factor: 11.205

2. Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells.

Authors: Keiko Muguruma; Ayaka Nishiyama; Hideshi Kawakami; Kouichi Hashimoto; Yoshiki Sasai
Journal: Cell Rep Date: 2015-01-29 Impact factor: 9.423

3. Next-generation regenerative medicine: organogenesis from stem cells in 3D culture.

Authors: Yoshiki Sasai
Journal: Cell Stem Cell Date: 2013-05-02 Impact factor: 24.633

4. FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders.

Authors: Jessica Mariani; Gianfilippo Coppola; Ping Zhang; Alexej Abyzov; Lauren Provini; Livia Tomasini; Mariangela Amenduni; Anna Szekely; Dean Palejev; Michael Wilson; Mark Gerstein; Elena L Grigorenko; Katarzyna Chawarska; Kevin A Pelphrey; James R Howe; Flora M Vaccarino
Journal: Cell Date: 2015-07-16 Impact factor: 41.582

5. Modeling human cortical development in vitro using induced pluripotent stem cells.

Authors: Jessica Mariani; Maria Vittoria Simonini; Dean Palejev; Livia Tomasini; Gianfilippo Coppola; Anna M Szekely; Tamas L Horvath; Flora M Vaccarino
Journal: Proc Natl Acad Sci U S A Date: 2012-07-03 Impact factor: 11.205

6. Directed differentiation of telencephalic precursors from embryonic stem cells.

Authors: Kiichi Watanabe; Daisuke Kamiya; Ayaka Nishiyama; Tomoko Katayama; Satoshi Nozaki; Hiroshi Kawasaki; Yasuyoshi Watanabe; Kenji Mizuseki; Yoshiki Sasai
Journal: Nat Neurosci Date: 2005-02-06 Impact factor: 24.884

7. Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure.

Authors: Xuyu Qian; Ha Nam Nguyen; Mingxi M Song; Christopher Hadiono; Sarah C Ogden; Christy Hammack; Bing Yao; Gregory R Hamersky; Fadi Jacob; Chun Zhong; Ki-Jun Yoon; William Jeang; Li Lin; Yujing Li; Jai Thakor; Daniel A Berg; Ce Zhang; Eunchai Kang; Michael Chickering; David Nauen; Cheng-Ying Ho; Zhexing Wen; Kimberly M Christian; Pei-Yong Shi; Brady J Maher; Hao Wu; Peng Jin; Hengli Tang; Hongjun Song; Guo-Li Ming
Journal: Cell Date: 2016-04-22 Impact factor: 41.582

8. Cerebral organoids model human brain development and microcephaly.

Authors: Madeline A Lancaster; Magdalena Renner; Carol-Anne Martin; Daniel Wenzel; Louise S Bicknell; Matthew E Hurles; Tessa Homfray; Josef M Penninger; Andrew P Jackson; Juergen A Knoblich
Journal: Nature Date: 2013-08-28 Impact factor: 49.962

9. Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells.

Authors: Chikafumi Ozone; Hidetaka Suga; Mototsugu Eiraku; Taisuke Kadoshima; Shigenobu Yonemura; Nozomu Takata; Yutaka Oiso; Takashi Tsuji; Yoshiki Sasai
Journal: Nat Commun Date: 2016-01-14 Impact factor: 14.919

10. Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue.

Authors: Hideya Sakaguchi; Taisuke Kadoshima; Mika Soen; Nobuhiro Narii; Yoshihito Ishida; Masatoshi Ohgushi; Jun Takahashi; Mototsugu Eiraku; Yoshiki Sasai
Journal: Nat Commun Date: 2015-11-17 Impact factor: 14.919

10 in total

2 in total

Review 1. Neurotropic Effects of SARS-CoV-2 Modeled by the Human Brain Organoids.

Authors: Anand Ramani; Abida-Islam Pranty; Jay Gopalakrishnan
Journal: Stem Cell Reports Date: 2021-02-12 Impact factor: 7.765

Review 2. Three-Dimensional Culture Systems for Dissecting Notch Signalling in Health and Disease.

Authors: Guya Diletta Marconi; Cristina Porcheri; Oriana Trubiani; Thimios A Mitsiadis
Journal: Int J Mol Sci Date: 2021-11-19 Impact factor: 5.923

2 in total