Literature DB >> 3117347

Pseudoatrophy of the brain with valproic acid monotherapy.

R S McLachlan1.   

Abstract

A patient is described who, while on valproic acid monotherapy, developed reversible shrinkage of the brain, documented by computerized tomography with associated cognitive deficit. Although pseudoatrophy has been reported with steroid therapy, this is the first implication of an anticonvulsant drug in the etiology of that condition.

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Year:  1987        PMID： 3117347     DOI： 10.1017/s0317167100026640

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN： 0317-1671            Impact factor:   2.104


  6 in total

1.  Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease.

Authors:  Pierre N Tariot; Lon S Schneider; Jeffrey Cummings; Ronald G Thomas; Rema Raman; Laura J Jakimovich; Rebekah Loy; Barbara Bartocci; Adam Fleisher; M Saleem Ismail; Anton Porsteinsson; Michael Weiner; Clifford R Jack; Leon Thal; Paul S Aisen
Journal:  Arch Gen Psychiatry       Date:  2011-08

2.  Neurotoxicity of combination chemotherapy with procarbazine, CCNU and vincristine (PCV) for recurrent glioma.

Authors:  T J Postma; C J van Groeningen; R J Witjes; J G Weerts; J H Kralendonk; J J Heimans
Journal:  J Neurooncol       Date:  1998-05       Impact factor: 4.130

3.  Reversible brain atrophy in anti-NMDA receptor encephalitis: a long-term observational study.

Authors:  Takahiro Iizuka; Shintaro Yoshii; Shinichi Kan; Junichi Hamada; Josep Dalmau; Fumihiko Sakai; Hideki Mochizuki
Journal:  J Neurol       Date:  2010-06-02       Impact factor: 4.849

4.  Deformation-based morphometry of prospective neurodevelopmental changes in new onset paediatric epilepsy.

Authors:  Duygu Tosun; Kevin Dabbs; Rochelle Caplan; Prabha Siddarth; Arthur Toga; Michael Seidenberg; Bruce Hermann
Journal:  Brain       Date:  2011-03-11       Impact factor: 13.501

5.  Cerebellar atrophy in a child with valproate toxicity.

Authors:  Vidya B Ghosh; Seema Kapoor; Anjali Prakash; Sinchana Bhatt
Journal:  Indian J Pediatr       Date:  2011-01-19       Impact factor: 1.967

6.  Valproate Use Is Associated With Posterior Cortical Thinning and Ventricular Enlargement in Epilepsy Patients.

Authors:  Manuela Tondelli; Anna Elisabetta Vaudano; Sanjay M Sisodiya; Stefano Meletti
Journal:  Front Neurol       Date:  2020-07-02       Impact factor: 4.003
  6 in total

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