Abhishek S Chitnis1, Mollie Vanderkarr2, Charisse Sparks3, Jonathan McGlohorn4, Chantal E Holy1. 1. Medical Devices Epidemiology, Real World Data Sciences, Johnson & Johnson, New Brunswick, NJ 08901, USA. 2. Health Economics Market Access, DePuy Synthes Orthopaedics, West Chester, PA 19380, USA. 3. Medical Affairs, DePuy Synthes Orthopaedics, West Chester, PA 19380, USA. 4. Clinical Research, DePuy Synthes Switzerland, Solothurn 4528, Switzerland.
Abstract
Aim: To estimate rates of fracture-related infection (FRI) and nonunion and assess the healthcare burden associated with FRI among patients with open reduction and internal fixation (ORIF) for Type III open tibial shaft fractures (TSFs). Methods: Patients with type III TSF requiring ORIF were identified using MarketScan® Database. Healthcare utilization and total costs were compared using generalized linear models. Results: The rates of FRI and nonunion were 35.99 and 36.94%, respectively, at 365 days. Patients with FRI had a significantly higher rate of readmission, emergency room visit and total healthcare costs compared with patients without FRI. Conclusion: Patients with an ORIF procedure for Type III TSF have a high risk of FRI and nonunion and; FRI significantly increased the healthcare burden.
Aim: To estimate rates of fracture-related infection (FRI) and nonunion and assess the healthcare burden associated with FRI among patients with open reduction and internal fixation (ORIF) for Type III open tibial shaft fractures (TSFs). Methods:Patients with type III TSF requiring ORIF were identified using MarketScan® Database. Healthcare utilization and total costs were compared using generalized linear models. Results: The rates of FRI and nonunion were 35.99 and 36.94%, respectively, at 365 days. Patients with FRI had a significantly higher rate of readmission, emergency room visit and total healthcare costs compared with patients without FRI. Conclusion:Patients with an ORIF procedure for Type III TSF have a high risk of FRI and nonunion and; FRI significantly increased the healthcare burden.
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Keywords:
Gustilo Anderson Type III open fractures; costs; fracture-related infection; healthcare utilization; nonunion; open reduction and internal fixation; tibia shaft fractures