Manisha Pahwa1, France Labrèche2,3, Joanne Kim1,4, M Anne Harris1,5,6, Chaojie Song1, Cheryl E Peters1,7,8,9, Victoria H Arrandale1,6, Hugh Davies1,7,10, Christopher B McLeod10,11, Paul A Demers1,6,7,10. 1. Occupational Cancer Research Centre, Prevention and Cancer Control, Cancer Care Ontario, Toronto, Ontario, Canada. 2. Institut de recherche Robert-Sauvé en santé et en sécurité du travail, Montréal, Quebec, Canada. 3. Department of Environmental and Occupational Health, School of Public Health, Université de Montréal, Montréal, Quebec, Canada. 4. Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Quebec, Canada. 5. School of Occupational and Public Health, Faculty of Community Services, Ryerson University, Toronto, Ontario, Canada. 6. Dalla Lana School of Public Health, Division of Occupational and Environmental Health, University of Toronto, Toronto, Ontario, Canada. 7. CAREX Canada, Simon Fraser University, Burnaby, British Columbia, Canada. 8. Cancer Epidemiology and Prevention Research, Alberta Health Services, CancerControl Alberta, Calgary, Alberta, Canada. 9. Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. 10. School of Population and Public Health, Division of Occupational and Environmental Health, University of British Columbia, Vancouver, British Columbia, Canada. 11. Institute for Work & Health, Toronto, Ontario, Canada.
Abstract
BACKGROUND: We estimated the proportion and number of female breast cancer cases in Canada attributable to night shift work, a probable cause of breast cancer. METHODS: Levin's equation was used to calculate population attributable fractions (PAFs) among Canadian women who ever worked night/rotating shifts from 1961 to 2000, accounting for labor turnover and survival to the year 2011. The calculated PAFs were applied to 2011 Canadian breast cancer incidence statistics to obtain the number of attributable cases. RESULTS: Approximately 1.5 million women ever worked night/rotating shifts during 1961-2000 and survived to 2011. The PAFs ranged from 2.0% (95% confidence interval [CI]: 1.4-6.2) to 5.2% (95% CI: 3.7-13.6), and 470 to 1200 incident breast cancer cases in 2011 were likely due to shift work, of which 38% would have been diagnosed among women in health-related occupations. CONCLUSIONS: More research is needed to increase the certainty of this association, but current evidence supports workplace-based prevention.
BACKGROUND: We estimated the proportion and number of female breast cancer cases in Canada attributable to night shift work, a probable cause of breast cancer. METHODS: Levin's equation was used to calculate population attributable fractions (PAFs) among Canadian women who ever worked night/rotating shifts from 1961 to 2000, accounting for labor turnover and survival to the year 2011. The calculated PAFs were applied to 2011 Canadian breast cancer incidence statistics to obtain the number of attributable cases. RESULTS: Approximately 1.5 million women ever worked night/rotating shifts during 1961-2000 and survived to 2011. The PAFs ranged from 2.0% (95% confidence interval [CI]: 1.4-6.2) to 5.2% (95% CI: 3.7-13.6), and 470 to 1200 incident breast cancer cases in 2011 were likely due to shift work, of which 38% would have been diagnosed among women in health-related occupations. CONCLUSIONS: More research is needed to increase the certainty of this association, but current evidence supports workplace-based prevention.
Authors: Marta Szkiela; Ewa Kusideł; Teresa Makowiec-Dąbrowska; Dorota Kaleta Journal: Int J Environ Res Public Health Date: 2021-04-26 Impact factor: 3.390
Authors: E Manouchehri; A Taghipour; V Ghavami; A Ebadi; F Homaei; R Latifnejad Roudsari Journal: BMC Womens Health Date: 2021-03-02 Impact factor: 2.809