Literature DB >> 31172266

[Health care and disease burden in persons with axial spondyloarthritis in Germany].

H Haibel1, I Redeker2,3, A Zink3, J Callhoff3, U Marschall4, F Hoffmann5, J Sieper2, D Poddubnyy2.   

Abstract

BACKGROUND: Only very few data are available on the comprehensive care in patients with axial spondylarthritis (axSpA), one of the most frequent inflammatory rheumatic disease.
OBJECTIVE: Description of the comprehensive care and common prescription patterns of medications and other therapies in patients with axSpA depending on the type of medical care by rheumatologists or nonrheumatologists.
METHODS: A cross-sectional analysis was performed based on claims data of the BARMER health insurance company (in 2015) and a questionnaire, which was sent to a representative sample of patients with axSpA (International Classification of Diseases, 10th revision, German modification, ICD-10-GM, code M45) aged 18-79 years. A stratified sample of 5000 patients was used. The patients received a postal questionnaire including questions regarding the disease, health-related and psychological parameters and socioeconomic factors. Claims data consisted of demographic factors, medicinal and nonmedicinal treatment and the extra-articular manifestations inflammatory bowel disease, psoriasis and uveitis.
RESULTS: A total of 1741 patients (mean age 55.9 years, female 46.4%, 86.2% Human Leucocyte Antigen[HLA]-B27 positive) confirmed the diagnosis and answered the questionnaire. The mean Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was 4.5 and the mean Bath Ankylosing Spondylitis Functional Index (BASFI) 4.1. Of the patients 46% were treated by rheumatologists. There was a substantial difference between patients in rheumatological care and those who were not in rheumatological care regarding prescriptions for drug treatment of axSpA (91.8% versus 66.4%). This difference was especially prominent for prescriptions of biologic disease-modifying antirheumatic drugs: 34.1% of patients in rheumatological care versus 3.1% of patients treated by nonrheumatologists (p < 0.0001), despite similar disease activity in both groups.
CONCLUSION: The data show that the majority of patients diagnosed with axSpA did not receive regular care from rheumatologists. This seemed to be associated with insufficient medicinal care at least in some of these patients.

Entities:  

Keywords:  Ankylosing spondylitis; Burden of disease; Diagnostics; Drug treatment; Health insurance data; Medical care

Mesh:

Substances:

Year:  2019        PMID: 31172266     DOI: 10.1007/s00393-019-0650-7

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  16 in total

1.  [Age at disease onset and delayed diagnosis of spondyloarthropathies].

Authors:  E Feldtkeller
Journal:  Z Rheumatol       Date:  1999-02       Impact factor: 1.372

2.  Prevalence of ankylosing spondylitis in males and females in a young middle-aged population of Tromsø, northern Norway.

Authors:  J T Gran; G Husby; M Hordvik
Journal:  Ann Rheum Dis       Date:  1985-06       Impact factor: 19.103

3.  [Memorandum of the German Society for Rheumatology on the quality of treatment in rheumatology - Update 2016].

Authors:  A Zink; J Braun; E Gromnica-Ihle; D Krause; H J Lakomek; W Mau; U Müller-Ladner; J Rautenstrauch; C Specker; M Schneider
Journal:  Z Rheumatol       Date:  2017-04       Impact factor: 1.372

4.  Baseline radiographic damage, elevated acute-phase reactant levels, and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis.

Authors:  Denis Poddubnyy; Hildrun Haibel; Joachim Listing; Elisabeth Märker-Hermann; Henning Zeidler; Jürgen Braun; Joachim Sieper; Martin Rudwaleit
Journal:  Arthritis Rheum       Date:  2012-05

Review 5.  Scientific contributions of ankylosing spondylitis patient advocacy groups.

Authors:  E Feldtkeller; J Bruckel; M A Khan
Journal:  Curr Opin Rheumatol       Date:  2000-07       Impact factor: 5.006

Review 6.  Axial spondyloarthritis.

Authors:  Joachim Sieper; Denis Poddubnyy
Journal:  Lancet       Date:  2017-01-20       Impact factor: 79.321

7.  How to diagnose axial spondyloarthritis early.

Authors:  M Rudwaleit; D van der Heijde; M A Khan; J Braun; J Sieper
Journal:  Ann Rheum Dis       Date:  2004-05       Impact factor: 19.103

8.  The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection.

Authors:  M Rudwaleit; D van der Heijde; R Landewé; J Listing; N Akkoc; J Brandt; J Braun; C T Chou; E Collantes-Estevez; M Dougados; F Huang; J Gu; M A Khan; Y Kirazli; W P Maksymowych; H Mielants; I J Sørensen; S Ozgocmen; E Roussou; R Valle-Oñate; U Weber; J Wei; J Sieper
Journal:  Ann Rheum Dis       Date:  2009-03-17       Impact factor: 19.103

9.  Functional relevance of radiographic spinal progression in axial spondyloarthritis: results from the GErman SPondyloarthritis Inception Cohort.

Authors:  Denis Poddubnyy; Joachim Listing; Hildrun Haibel; Sven Knüppel; Martin Rudwaleit; Joachim Sieper
Journal:  Rheumatology (Oxford)       Date:  2018-04-01       Impact factor: 7.580

10.  Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force.

Authors:  Josef S Smolen; Jürgen Braun; Maxime Dougados; Paul Emery; Oliver Fitzgerald; Philip Helliwell; Arthur Kavanaugh; Tore K Kvien; Robert Landewé; Thomas Luger; Philip Mease; Ignazio Olivieri; John Reveille; Christopher Ritchlin; Martin Rudwaleit; Monika Schoels; Joachim Sieper; Martinus de Wit; Xenofon Baraliakos; Neil Betteridge; Ruben Burgos-Vargas; Eduardo Collantes-Estevez; Atul Deodhar; Dirk Elewaut; Laure Gossec; Merryn Jongkees; Mara Maccarone; Kurt Redlich; Filip van den Bosch; James Cheng-Chung Wei; Kevin Winthrop; Désirée van der Heijde
Journal:  Ann Rheum Dis       Date:  2013-06-08       Impact factor: 19.103

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  8 in total

1.  [Cost of illness in axial spondylarthritis for patients with and without tumor necrosis factor inhibitor treatment: results of a routine data analysis].

Authors:  I Redeker; J Callhoff; F Hoffmann; J Saam; H Haibel; J Sieper; A Zink; D Poddubnyy
Journal:  Z Rheumatol       Date:  2020-02       Impact factor: 1.372

2.  [Apps in rheumatology : Is there a need for an app in therapy for axial spondyloarthritis?]

Authors:  Patrick-Pascal Strunz; Maxime Le Maire; Tobias Heusinger; Ludwig Hammel; Michael Gernert; Eva C Schwaneck; Johanna Callhoff; Jan Portegys; Marc Schmalzing; Hans-Peter Tony; Matthias Froehlich
Journal:  Z Rheumatol       Date:  2021-10-07       Impact factor: 1.372

Review 3.  Treat-to-target in axial spondyloarthritis - what about physical function and activity?

Authors:  Jürgen Braun; Xenofon Baraliakos; Uta Kiltz
Journal:  Nat Rev Rheumatol       Date:  2021-07-26       Impact factor: 20.543

4.  [Prescription of analgesics in patients with rheumatic diseases in Germany : A claims data analysis. German version].

Authors:  K Albrecht; U Marschall; J Callhoff
Journal:  Z Rheumatol       Date:  2021-02-26       Impact factor: 1.372

5.  The impact of extra-musculoskeletal manifestations on disease activity, functional status, and treatment patterns in patients with axial spondyloarthritis: results from a nationwide population-based study.

Authors:  Imke Redeker; Britta Siegmund; Kamran Ghoreschi; Uwe Pleyer; Johanna Callhoff; Falk Hoffmann; Ursula Marschall; Hildrun Haibel; Joachim Sieper; Angela Zink; Denis Poddubnyy
Journal:  Ther Adv Musculoskelet Dis       Date:  2020-11-21       Impact factor: 5.346

6.  [Prescription frequency of physical therapy for inflammatory rheumatic diseases].

Authors:  Katinka Albrecht; Ursula Marschall; Angela Zink; Johanna Callhoff
Journal:  Z Rheumatol       Date:  2022-03-22       Impact factor: 1.530

7.  The prevalence and impact of comorbidities on patients with axial spondyloarthritis: results from a nationwide population-based study.

Authors:  Imke Redeker; Johanna Callhoff; Falk Hoffmann; Ursula Marschall; Hildrun Haibel; Joachim Sieper; Angela Zink; Denis Poddubnyy
Journal:  Arthritis Res Ther       Date:  2020-09-10       Impact factor: 5.156

8.  Prescription of analgesics in patients with rheumatic diseases in Germany : A claims data analysis.

Authors:  K Albrecht; U Marschall; J Callhoff
Journal:  Z Rheumatol       Date:  2021-04-07       Impact factor: 1.372

  8 in total

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