Ashley N Battarbee1, Angelica V Glover1, Catherine J Vladutiu1, Cynthia Gyamfi-Bannerman2, Sofia Aliaga3, Tracy A Manuck1, Kim A Boggess1. 1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. 2. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY, USA. 3. Division of Neonatology, Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Abstract
OBJECTIVE: To identify risk factors associated with neonatal intermediate or intensive care unit (NICU) stay ≥3 days among women with threatened late preterm birth (PTB). STUDY DESIGN: Secondary analysis of women with nonanomalous, singleton gestations enrolled in multicenter trial ofbetamethasone versus placebo for late PTB. Maternal and obstetric characteristics at time of presentation with threatened PTB were compared between those with and without NICU stay ≥3 days. Multivariable logistic regression identified risk factors for NICU stay ≥3 days. RESULT: Of 2795 eligible mother-neonate dyads, 962 (34%) had NICU stay ≥3 days. Gestational age and fetal growth restriction as the reason for threatened PTB had the strongest association with NICU stay ≥3 days in the final model (AUC 0.76). CONCLUSION:Maternal and obstetric characteristics at the time of admission for threatened late PTB should be considered when counseling patients about the probability of NICU stay ≥3 days.
RCT Entities:
OBJECTIVE: To identify risk factors associated with neonatal intermediate or intensive care unit (NICU) stay ≥3 days among women with threatened late preterm birth (PTB). STUDY DESIGN: Secondary analysis of women with nonanomalous, singleton gestations enrolled in multicenter trial of betamethasone versus placebo for late PTB. Maternal and obstetric characteristics at time of presentation with threatened PTB were compared between those with and without NICU stay ≥3 days. Multivariable logistic regression identified risk factors for NICU stay ≥3 days. RESULT: Of 2795 eligible mother-neonate dyads, 962 (34%) had NICU stay ≥3 days. Gestational age and fetal growth restriction as the reason for threatened PTB had the strongest association with NICU stay ≥3 days in the final model (AUC 0.76). CONCLUSION: Maternal and obstetric characteristics at the time of admission for threatened late PTB should be considered when counseling patients about the probability of NICU stay ≥3 days.
Entities:
Keywords:
Antenatal corticosteroids; betamethasone; late preterm; neonatal intensive care unit; preterm birth
Authors: Judith U Hibbard; Isabelle Wilkins; Liping Sun; Kimberly Gregory; Shoshana Haberman; Matthew Hoffman; Michelle A Kominiarek; Uma Reddy; Jennifer Bailit; D Ware Branch; Ronald Burkman; Victor Hugo Gonzalez Quintero; Christos G Hatjis; Helain Landy; Mildred Ramirez; Paul VanVeldhuisen; James Troendle; Jun Zhang Journal: JAMA Date: 2010-07-28 Impact factor: 56.272
Authors: Cynthia Gyamfi-Bannerman; Elizabeth A Thom; Sean C Blackwell; Alan T N Tita; Uma M Reddy; George R Saade; Dwight J Rouse; David S McKenna; Erin A S Clark; John M Thorp; Edward K Chien; Alan M Peaceman; Ronald S Gibbs; Geeta K Swamy; Mary E Norton; Brian M Casey; Steve N Caritis; Jorge E Tolosa; Yoram Sorokin; J Peter VanDorsten; Lucky Jain Journal: N Engl J Med Date: 2016-02-04 Impact factor: 91.245