Literature DB >> 31170827

Implementing an integrated community based health systems strengthening approach to improve HIV survival in Northern Togo.

Kevin P Fiori1,2,3, Hayley M Belli4, Molly E Lauria3, Lisa R Hirschhorn3,5, Jennifer Schechter6, Emily Hansman6, Nandita Rajshekhar6, Venance Katin6,7, Sesso Gbeleou6, Meskerem Grunitsky-Bekele6, Vincent Palokinam Pitche8.   

Abstract

To disseminate lessons learned from the implementation experience of a public-private sector partnership, we describe a comprehensive HIV/AIDS program including 5-year survival outcomes for individuals who initiated antiretroviral therapy (ART) treatment in Togo from 2010 to 2015. A retrospective case study analysis was conducted from a cohort of patients receiving ART at an HIV/AIDS care clinic in Kara Region, Togo. Kaplan-Meier curves with Log rank tests were used to compare estimated survival curves by demographic and clinical characteristics. Associations were described between survival probability and age, gender, World Health Organization (WHO) disease stage, and timing of ART initiation. Cox proportional hazard model was used to determine predictors of mortality. After approximately five-years since ART initiation (1780 days), there were 114 deaths, with a survival probability of 75.3% (95% CI: 70.3-80.6%). Participants with advanced WHO disease stage were more likely at risk of death relative to patients categorized as WHO Stage 1, with Stage 4 approximately 9 times more likely (aHR 9.22, 95% CI 4.29-19.84). Our study suggests that delivering comprehensive HIV care through a private-public partnership may serve as a model to expand and improve HIV/AIDS care as well as high quality primary care.

Entities:  

Keywords:  HIV/AIDS; Health systems strengthening; Togo; community health workers

Mesh:

Substances:

Year:  2019        PMID: 31170827      PMCID: PMC7357197          DOI: 10.1080/09540121.2019.1626342

Source DB:  PubMed          Journal:  AIDS Care        ISSN: 0954-0121


  22 in total

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Journal:  J Acquir Immune Defic Syndr       Date:  2012-02-01       Impact factor: 3.731

2.  Excellent clinical outcomes and high retention in care among adults in a community-based HIV treatment program in rural Rwanda.

Authors:  Michael L Rich; Ann C Miller; Peter Niyigena; Molly F Franke; Jean Bosco Niyonzima; Adrienne Socci; Peter C Drobac; Massudi Hakizamungu; Alishya Mayfield; Robert Ruhayisha; Henry Epino; Sara Stulac; Corrado Cancedda; Adolph Karamaga; Saleh Niyonzima; Chase Yarbrough; Julia Fleming; Cheryl Amoroso; Joia Mukherjee; Megan Murray; Paul Farmer; Agnes Binagwaho
Journal:  J Acquir Immune Defic Syndr       Date:  2012-03-01       Impact factor: 3.731

3.  Mortality and causes of death in adults receiving highly active antiretroviral therapy in Senegal: a 7-year cohort study.

Authors:  Jean-François Etard; Ibrahima Ndiaye; Marion Thierry-Mieg; Ndèye Fatou Ngom Guèye; Pape Mandoumbé Guèye; Isabelle Lanièce; Allé Baba Dieng; Assane Diouf; Christian Laurent; Souleymane Mboup; Papa Salif Sow; Eric Delaporte
Journal:  AIDS       Date:  2006-05-12       Impact factor: 4.177

4.  Mortality among people living with HIV on antiretroviral treatment in Bali, Indonesia: incidence and predictors.

Authors:  Sri Utami; Anak Agung Sagung Sawitri; Luh Putu Lila Wulandari; I Wayan Gede Artawan Eka Putra; Putu Ayu Swandewi Astuti; Dewa Nyoman Wirawan; Louise Causer; Bradley Mathers
Journal:  Int J STD AIDS       Date:  2017-02-15       Impact factor: 1.359

5.  Improved retention associated with community-based accompaniment for antiretroviral therapy delivery in rural Rwanda.

Authors:  Molly F Franke; Felix Kaigamba; Adrienne R Socci; Massudi Hakizamungu; Anita Patel; Emmanuel Bagiruwigize; Peter Niyigena; Kelly D C Walker; Henry Epino; Agnes Binagwaho; Joia Mukherjee; Paul E Farmer; Michael L Rich
Journal:  Clin Infect Dis       Date:  2012-12-18       Impact factor: 9.079

6.  5-year survival of patients with AIDS receiving antiretroviral therapy in Haiti.

Authors:  Paul Leger; Macarthur Charles; Patrice Severe; Cynthia Riviere; Jean William Pape; Daniel W Fitzgerald
Journal:  N Engl J Med       Date:  2009-08-20       Impact factor: 91.245

7.  Advanced HIV disease at entry into HIV care and initiation of antiretroviral therapy during 2006-2011: findings from four sub-saharan African countries.

Authors:  Maria Lahuerta; Yingfeng Wu; Susie Hoffman; Batya Elul; Sarah Gorrell Kulkarni; Robert H Remien; Harriet Nuwagaba-Biribonwoha; Wafaa El-Sadr; Denis Nash
Journal:  Clin Infect Dis       Date:  2013-11-05       Impact factor: 9.079

8.  Factors associated with attrition, mortality, and loss to follow up after antiretroviral therapy initiation: data from an HIV cohort study in India.

Authors:  Gerardo Alvarez-Uria; Praveen K Naik; Raghavakalyan Pakam; Manoranjan Midde
Journal:  Glob Health Action       Date:  2013-09-12       Impact factor: 2.640

9.  Stigmatization of people living with HIV/AIDS by healthcare workers at a tertiary hospital in KwaZulu-Natal, South Africa: a cross-sectional descriptive study.

Authors:  Temitayo O Famoroti; Lucy Fernandes; Sylvester C Chima
Journal:  BMC Med Ethics       Date:  2013-12-19       Impact factor: 2.652

10.  Community case management of childhood illness in sub-Saharan Africa - findings from a cross-sectional survey on policy and implementation.

Authors:  Kumanan Rasanathan; Maria Muñiz; Salina Bakshi; Meghan Kumar; Agnes Solano; Wanjiku Kariuki; Asha George; Mariame Sylla; Rory Nefdt; Mark Young; Theresa Diaz
Journal:  J Glob Health       Date:  2014-12       Impact factor: 4.413

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  1 in total

1.  Assessing the Integrated Community-Based Health Systems Strengthening initiative in northern Togo: a pragmatic effectiveness-implementation study protocol.

Authors:  Molly E Lauria; Kevin P Fiori; Heidi E Jones; Sesso Gbeleou; Komlan Kenkou; Sibabe Agoro; Abdourahmane Diparidé Agbèrè; Kelly D Lue; Lisa R Hirschhorn
Journal:  Implement Sci       Date:  2019-10-16       Impact factor: 7.327

  1 in total

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