Lina Ma1, Frederick A Jakobiec1, Thaddeus P Dryja1. 1. a David G Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary , Harvard Medical School , Boston , MA , USA.
Abstract
Purpose: To review the value of next-generation sequencing (NGS) in identifying the pathogens which cause ocular infections, thereby facilitating prompt initiation of treatment with an optimal anti-microbial regimen. Both contemporary and futuristic approaches to identifying pathogens in ocular infections are covered in this brief overview. Methods: Review of the peer reviewed literature on conventional and advanced methods as applied to the diagnosis of infectious diseases of the eye. Conclusion: NGS is a novel technology for identifying the pathogens responsible for ocular infections with the potential to improve the accuracy and speed of diagnosis and hastening the selection of the best therapy.
Purpose: To review the value of next-generation sequencing (NGS) in identifying the pathogens which cause ocular infections, thereby facilitating prompt initiation of treatment with an optimal anti-microbial regimen. Both contemporary and futuristic approaches to identifying pathogens in ocular infections are covered in this brief overview. Methods: Review of the peer reviewed literature on conventional and advanced methods as applied to the diagnosis of infectious diseases of the eye. Conclusion: NGS is a novel technology for identifying the pathogens responsible for ocular infections with the potential to improve the accuracy and speed of diagnosis and hastening the selection of the best therapy.
Authors: Darren S J Ting; Bhavesh P Gopal; Rashmi Deshmukh; Gerami D Seitzman; Dalia G Said; Harminder S Dua Journal: Ocul Surf Date: 2021-11-13 Impact factor: 5.033
Authors: Mihail Zemba; Otilia-Maria Dumitrescu; Andreea-Elena Dimirache; Daniel Constantin Branisteanu; Florian Balta; Marian Burcea; Andreea Dana Moraru; Sinziana Gradinaru Journal: Exp Ther Med Date: 2021-12-13 Impact factor: 2.447