Literature DB >> 31169248

Primary mucoepidermoid carcinoma of the bulbar conjunctiva.

Bodhisattwa Dutta1, Nibedita Biswas2, Rumeli Roy2, Asit Ranjan Deb2.   

Abstract

A 58-year-old male presented with redness for 1 year and dimness of vision for 2 years in his left eye. Excision biopsy from an inferotemporal conjunctival mass revealed high-grade mucoepidermoid carcinoma (MEC) with lymphovascular invasion and positive margins. The tumor bed was irradiated to 80 Gy using strontium 90 β-applicator. After 13 months, fine-needle aspiration cytology from a suspicious preauricular lymphadenopathy found metastatic cells. Ipsilateral supra-omohyoid neck dissection showed three positive nodes out of 15, and the left neck was irradiated. He is disease free at present, 12 months from external beam radiation therapy completion. With 48 cases reported in the literature, conjunctival MEC remains a rare condition, possibly in part due to clinicopathological underdiagnosis. This is unfortunate, given that this cancer is more aggressive, has a poorer prognosis, and warrants more vigorous treatment than squamous cell carcinoma, which it may be misdiagnosed as in the absence of appropriate staining and pathological review.

Entities:  

Keywords:  Carcinoma; conjunctiva; mucoepidermoid; strontium 90; β-irradiation

Mesh:

Year:  2019        PMID: 31169248     DOI: 10.4103/jcrt.JCRT_926_17

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN: 1998-4138            Impact factor:   1.805


  2 in total

1.  Conjunctival 'mucoepidermoid carcinoma' revisited: a revision of terminology, based on morphologic, immunohistochemical and molecular findings of 14 cases, and the 2018 WHO Classification of Tumours of the Eye.

Authors:  Hardeep S Mudhar; Tatyana Milman; Paul J L Zhang; Carol L Shields; Ralph C Eagle; Sara E Lally; Jerry A Shields; Sachin M Salvi; Paul A Rundle; Jennifer Tan; Ian G Rennie
Journal:  Mod Pathol       Date:  2020-01-13       Impact factor: 7.842

2.  A Rare Case of Cutaneous Mucoepidermoid Carcinoma of the Eyelid: A Case Report and Literature Review.

Authors:  Robin Su; Ayad Abrou; Michael Abowd
Journal:  Case Rep Ophthalmol       Date:  2021-05-10
  2 in total

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