Literature DB >> 31169236

Clinicopathological analysis of extracranial head and neck schwannoma: A case series.

Preeti Sharma1, Sufian Zaheer1, Surbhi Goyal1, Charanjeet Ahluwalia1, Ankur Goyal2, Geet Bhuyan1, Ashish Kumar Mandal1.   

Abstract

BACKGROUND: Extracranial head and neck schwannomas are rare tumors which are often clinically misdiagnosed. Preoperative diagnosis of these tumors is challenging but imperative for surgeons so as to avoid nerve damage during excision.
MATERIALS AND METHODS: Sixteen patients diagnosed with extracranial head and neck schwannomas over a period of 2 years were retrospectively analyzed. Clinical details including preoperative fine-needle aspiration cytology (FNAC) and/or computed tomography (CT)/magnetic resonance imaging (MRI) findings were retrieved. FNAC smears and formalin-fixed paraffin-embedded sections were evaluated.
RESULTS: Among these 16 tumors, 6 (37.5%) were located in the lateral aspect of neck, 4 (25%) in scalp, 2 (12.5%) in orbit, and one each (6.25%) in palate, tongue, submandibular gland and parotid gland. The mean patient age was 31.3 years. FNAC was performed in 14 cases, of which 8 cases (58.3%) showed features of benign nerve sheath tumor (BNST), two cases (14.2%) were inconclusive with possibility of mesenchymal lesion, two cases (14.2%) were inadequate, one case (8.3%) showed features suggestive of schwannoma, and a diagnosis of nerve sheath tumor inconclusive for malignancy was rendered in a single case. The sensitivity of FNAC in diagnosis of BNST was 71.4%. CT or MRI was performed in five cases, of which an accurate diagnosis was rendered only in one case of orbital schwannoma.
CONCLUSION: Imaging has a limited role in the preoperative diagnosis of head and neck schwannomas owing to nonspecific radiological features. Cellular aspirate smears are helpful in accurate diagnosis even at unusual locations.

Entities:  

Keywords:  Extracranial; S-100; fine-needle aspiration cytology; neurilemmoma; schwannoma

Mesh:

Year:  2019        PMID: 31169236     DOI: 10.4103/jcrt.JCRT_1125_16

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN: 1998-4138            Impact factor:   1.805


  4 in total

1.  Suprasternal Schwannoma: A Rare Site of Presentation.

Authors:  Mithula Murali; Shraddha Jain; Chandra Veer Singh; Ajinkya Sandbhor; Vaidehi Hande
Journal:  Cureus       Date:  2022-08-30

2.  Diagnosis and management of hypoglossal nerve-derived schwannoma in the floor of mouth: a case series.

Authors:  Jiayong Zhong; Zhihang Zhou; Yuhua Hu; Tongchao Zhao; Yu Yao; Laiping Zhong; Dongwang Zhu
Journal:  BMC Oral Health       Date:  2022-06-29       Impact factor: 3.747

3.  A Huge Carotid Space Schwannoma Arising from The Cervical Sympathetic Chain - A Case Report.

Authors:  Malek A Elsayed; Ahmed M Ibrahim; Mustafa A El Darawany; Mohamed A Ellabban
Journal:  Ann Maxillofac Surg       Date:  2021-07-24

4.  Preauricular Intraparotid Schwannoma: A Rare Presentation with Literature Review.

Authors:  Mun Bhawni Bagga; Dipti Bhatnagar; Shiva Katoch
Journal:  Contemp Clin Dent       Date:  2021-06-14
  4 in total

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