Literature DB >> 31168257

Surgical Management of Carcinoma Vulva-Case Series and Review of Literature.

Prerna Lakhwani1, Priya Agarwal1, Juhi Agarwal Mahajan1, Ashish Goel1, Pankaj Pande1, Sandeep Mehta1, Kapil Kumar1.   

Abstract

The objective of this study was to study the risk factors, management protocols, and the outcome of vulvar cancer cases over a period of 2 years in a tertiary care hospital. This is a case series of early-stage vulvar cancer in the Department of Surgical Oncology in BL Kapur Superspeciality Hospital from Jan 2016 to date. Five patients with histologically proven diagnosis of early-stage vulvar cancer were included. The mean age for the diagnosis of vulvar cancer was 58 years and the peak incidence was seen in postmenopausal age group. All of the cases were squamous cell carcinomas in stage IB except one which was a basisquamous variant. All cases were treated primarily with surgery and vulvar flap reconstruction. Adjuvant therapy was not given in any case. Cases were followed from 6 months to date, and no recurrence noted. The limitations of the study were rarity of disease and less number of cases. As all the cases in our study were in early stage of disease (stages I and II), surgical treatment in the form of modified radical vulvectomy with B/L inguinofemoral lymph node dissection and oncoplastic procedure was the treatment modality chosen for all the patients.

Entities:  

Keywords:  Ca vulva; Early-stage vulval cancer; Inguinofemoral lymphadenectomy; Modified radical vulvectomy; Vulval oncoplasty

Year:  2019        PMID: 31168257      PMCID: PMC6527639          DOI: 10.1007/s13193-019-00887-9

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  9 in total

Review 1.  Prognostic implications of extranodal extension in node-positive squamous cell carcinoma of the vulva: A systematic review and meta-analysis.

Authors:  Claudio Luchini; Alessia Nottegar; Marco Solmi; Giuseppe Sergi; Enzo Manzato; Paola Capelli; Aldo Scarpa; Nicola Veronese
Journal:  Surg Oncol       Date:  2015-09-14       Impact factor: 3.279

Review 2.  A cohort study of vulvar cancer over a period of 10 years and review of literature.

Authors:  N Singh; N Negi; K Srivastava; G Agarwal
Journal:  Indian J Cancer       Date:  2016 Jul-Sep       Impact factor: 1.224

3.  Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths.

Authors:  Rebecca Siegel; Elizabeth Ward; Otis Brawley; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2011-06-17       Impact factor: 508.702

4.  Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: a multivariate analysis.

Authors:  John K Chan; Valerie Sugiyama; Huyen Pham; Mai Gu; Joanne Rutgers; Kathryn Osann; Michael K Cheung; Michael L Berman; Philip J Disaia
Journal:  Gynecol Oncol       Date:  2006-11-07       Impact factor: 5.482

5.  Preoperative intensity-modulated radiotherapy and chemotherapy for locally advanced vulvar carcinoma.

Authors:  Sushil Beriwal; Devin Coon; Dwight E Heron; Joseph L Kelley; Robert P Edwards; Paniti Sukumvanich; Kristin K Zorn; Thomas C Krivak
Journal:  Gynecol Oncol       Date:  2008-05       Impact factor: 5.482

6.  Sentinel node dissection is safe in the treatment of early-stage vulvar cancer.

Authors:  Ate G J Van der Zee; Maaike H Oonk; Joanne A De Hullu; Anca C Ansink; Ignace Vergote; René H Verheijen; Angelo Maggioni; Katja N Gaarenstroom; Peter J Baldwin; Eleonore B Van Dorst; Jacobus Van der Velden; Ralph H Hermans; Hans van der Putten; Pierre Drouin; Achim Schneider; Wim J Sluiter
Journal:  J Clin Oncol       Date:  2008-02-20       Impact factor: 44.544

7.  Demographic, clinical, and treatment trends among women diagnosed with vulvar cancer in the United States.

Authors:  A M Stroup; L C Harlan; E L Trimble
Journal:  Gynecol Oncol       Date:  2007-12-21       Impact factor: 5.482

8.  Postoperative complications after vulvectomy and inguinofemoral lymphadenectomy using separate groin incisions.

Authors:  K N Gaarenstroom; G G Kenter; J B Trimbos; I Agous; F Amant; A A W Peters; I Vergote
Journal:  Int J Gynecol Cancer       Date:  2003 Jul-Aug       Impact factor: 3.437

9.  Adjuvant therapy in lymph node-positive vulvar cancer: the AGO-CaRE-1 study.

Authors:  Sven Mahner; Julia Jueckstock; Felix Hilpert; Petra Neuser; Philipp Harter; Nikolaus de Gregorio; Annette Hasenburg; Jalid Sehouli; Annika Habermann; Peter Hillemanns; Sophie Fuerst; Hans-Georg Strauss; Klaus Baumann; Falk Thiel; Alexander Mustea; Werner Meier; Andreas du Bois; Lis-Femke Griebel; Linn Woelber
Journal:  J Natl Cancer Inst       Date:  2015-01-24       Impact factor: 13.506

  9 in total

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