Literature DB >> 31167898

Sex and the Single Fly: A Perspective on the Career of Bruce S. Baker.

Deborah J Andrew1, Elizabeth H Chen2,3,4, Devanand S Manoli5,6, Lisa C Ryner7, Michelle N Arbeitman8.   

Abstract

Bruce Baker, a preeminent Drosophila geneticist who made fundamental contributions to our understanding of the molecular genetic basis of sex differences, passed away July 1, 2018 at the age of 72. Members of Bruce's laboratory remember him as an intensely dedicated, rigorous, creative, deep-thinking, and fearless scientist. His trainees also remember his strong commitment to teaching students at every level. Bruce's career studying sex differences had three major epochs, where the laboratory was focused on: (1) sex determination and dosage compensation, (2) the development of sex-specific structures, and (3) the molecular genetic basis for sex differences in behavior. Several members of the Baker laboratory have come together to honor Bruce by highlighting some of the laboratory's major scientific contributions in these areas.
Copyright © 2019 by the Genetics Society of America.

Entities:  

Keywords:  Drosophila; behavior; development; doublesex; fruitless; genital disc; mRNA splicing; sex; sex determination; transformer

Mesh:

Year:  2019        PMID: 31167898      PMCID: PMC6553822          DOI: 10.1534/genetics.119.301928

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  100 in total

1.  Functional redundancy within roX1, a noncoding RNA involved in dosage compensation in Drosophila melanogaster.

Authors:  Carsten Stuckenholz; Victoria H Meller; Mitzi I Kuroda
Journal:  Genetics       Date:  2003-07       Impact factor: 4.562

2.  The muscle pattern of a segment of Drosophila may be determined by neurons and not by contributing myoblasts.

Authors:  P A Lawrence; P Johnston
Journal:  Cell       Date:  1986-05-23       Impact factor: 41.582

3.  The dosage compensation system of Drosophila is co-opted by newly evolved X chromosomes.

Authors:  I Marín; A Franke; G J Bashaw; B S Baker
Journal:  Nature       Date:  1996-09-12       Impact factor: 49.962

4.  roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males.

Authors:  Xinxian Deng; Victoria H Meller
Journal:  Genetics       Date:  2006-10-08       Impact factor: 4.562

Review 5.  Moving up the hierarchy: a hypothesis on the evolution of a genetic sex determination pathway.

Authors:  A S Wilkins
Journal:  Bioessays       Date:  1995-01       Impact factor: 4.345

6.  Allocation and specification of the genital disc precursor cells in Drosophila.

Authors:  Elizabeth H Chen; Audrey E Christiansen; Bruce S Baker
Journal:  Dev Biol       Date:  2005-05-15       Impact factor: 3.582

7.  The sex determination gene doublesex regulates the A/P organizer to direct sex-specific patterns of growth in the Drosophila genital imaginal disc.

Authors:  E L Keisman; A E Christiansen; B S Baker
Journal:  Dev Cell       Date:  2001-08       Impact factor: 12.270

8.  Initiation of dosage compensation in Drosophila embryos depends on expression of the roX RNAs.

Authors:  Victoria H Meller
Journal:  Mech Dev       Date:  2003-07       Impact factor: 1.882

9.  Control of sexual differentiation and behavior by the doublesex gene in Drosophila melanogaster.

Authors:  Elizabeth J Rideout; Anthony J Dornan; Megan C Neville; Suzanne Eadie; Stephen F Goodwin
Journal:  Nat Neurosci       Date:  2010-03-21       Impact factor: 24.884

10.  Genomic and functional studies of Drosophila sex hierarchy regulated gene expression in adult head and nervous system tissues.

Authors:  Thomas D Goldman; Michelle N Arbeitman
Journal:  PLoS Genet       Date:  2007-11       Impact factor: 5.917

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  1 in total

1.  Investigation of Drosophila fruitless neurons that express Dpr/DIP cell adhesion molecules.

Authors:  Savannah G Brovero; Julia C Fortier; Hongru Hu; Pamela C Lovejoy; Nicole R Newell; Colleen M Palmateer; Ruei-Ying Tzeng; Pei-Tseng Lee; Kai Zinn; Michelle N Arbeitman
Journal:  Elife       Date:  2021-02-22       Impact factor: 8.140

  1 in total

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